Synthesis of furans, pyrroles and pyridazines by a ruthenium-catalysed isomerisation of alkynediols and in situ cyclisation

S J Pridmore, P A Slatford, J E Taylor, M K Whittlesey, J M J Williams

Research output: Contribution to journalArticle

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Abstract

Alkyne-1,4-diols are readily available substrates which are isomerised to 1,4-diketones using Ru(PPh3)(3)(CO)H-2/xantphos as a catalyst. In situ cyclisation into furans, pyrroles and pyridazines has been achieved under suitable conditions. (C) 2009 Elsevier Ltd. All rights reserved.
LanguageEnglish
Pages8981-8986
Number of pages6
JournalTetrahedron
Volume65
Issue number44
DOIs
StatusPublished - 2009

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Pyridazines
Furans
Pyrroles
Alkynes
Ruthenium
Cyclization
Carbon Monoxide
Isomerization
Catalysts
Substrates
xantphos

Cite this

Synthesis of furans, pyrroles and pyridazines by a ruthenium-catalysed isomerisation of alkynediols and in situ cyclisation. / Pridmore, S J; Slatford, P A; Taylor, J E; Whittlesey, M K; Williams, J M J.

In: Tetrahedron, Vol. 65, No. 44, 2009, p. 8981-8986.

Research output: Contribution to journalArticle

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