Alkyne-1,4-diols are readily available substrates which are isomerised to 1,4-diketones using Ru(PPh3)(3)(CO)H-2/xantphos as a catalyst. In situ cyclisation into furans, pyrroles and pyridazines has been achieved under suitable conditions. (C) 2009 Elsevier Ltd. All rights reserved.
Pridmore, S. J., Slatford, P. A., Taylor, J. E., Whittlesey, M. K., & Williams, J. M. J. (2009). Synthesis of furans, pyrroles and pyridazines by a ruthenium-catalysed isomerisation of alkynediols and in situ cyclisation. Tetrahedron, 65(44), 8981-8986. https://doi.org/10.1016/j.tet.2009.06.108