Synthesis and characterization of magnetite/polyvinyl alcohol core–shell composite nanoparticles

Rajnish Kurchania, Sachin S. Sawant, Richard Ball

Research output: Contribution to journalArticle

14 Citations (Scopus)

Abstract

Magnetite (Fe3O4)/polyvinyl alcohol (PVA) core–shell composite nanoparticles were successfully synthesized using a coprecipitation of ferrous and ferric chloride followed by coating with PVA. The resulting nanoparticles were characterized using X-ray diffraction, Fourier Transform Infrared Spectroscopy, Transmission Electron Microscopy, X-ray photo electron spectroscopy, Zeta potential measurements, UV–Vis spectroscopy, Thermogravimetric Analysis, and Vibrating Sample
Magnetometry (VSM). The average particle size was 13 nm. The presence of characteristic functional groups of PVA around the core of magnetite nanoparticles was confirmed by FTIR spectroscopy while the amount of PVA (%) bound to it was estimated by TGA analysis. Zeta potential measurements made by dispersing dilute sonicated samples in a Phosphate Buffer Saline (PBS pH 7.4) confirmed that the particles were negatively charged. The stability and retention of the coating
material PVA in PBS (pH7.4) over a period of time were substantiated by UV–Vis spectroscopy. Room-temperature magnetic measurements were made with a VSM which demonstrated the superparamagnetic nature of the particles with higher saturation magnetization of 56.41 emu/g. Furthermore, in vitro cytocompatibility testing of Fe3O4/PVA core–shell composite nanoparticles was carried out on human cervix cancer cells. This confirmed a 97% cell viability with no significant cytotoxicity and thereby substantiated their biocompatibility.

Original languageEnglish
Pages (from-to)3208–3215
Number of pages8
JournalJournal of the American Ceramic Society
Volume97
Issue number10
Early online date24 Jul 2014
DOIs
Publication statusPublished - 15 Oct 2014

Fingerprint

Ferrosoferric Oxide
Polyvinyl Alcohol
Polyvinyl alcohols
Magnetite
magnetite
alcohol
shell
Nanoparticles
Composite materials
Zeta potential
Ultraviolet spectroscopy
FTIR spectroscopy
coating
Magnetite Nanoparticles
spectroscopy
Cells
Magnetite nanoparticles
Coatings
Magnetic variables measurement
Saturation magnetization

Cite this

Synthesis and characterization of magnetite/polyvinyl alcohol core–shell composite nanoparticles. / Kurchania, Rajnish; Sawant, Sachin S.; Ball, Richard.

In: Journal of the American Ceramic Society, Vol. 97, No. 10, 15.10.2014, p. 3208–3215.

Research output: Contribution to journalArticle

@article{b7fbb69430784e62918d563f2b88d836,
title = "Synthesis and characterization of magnetite/polyvinyl alcohol core–shell composite nanoparticles",
abstract = "Magnetite (Fe3O4)/polyvinyl alcohol (PVA) core–shell composite nanoparticles were successfully synthesized using a coprecipitation of ferrous and ferric chloride followed by coating with PVA. The resulting nanoparticles were characterized using X-ray diffraction, Fourier Transform Infrared Spectroscopy, Transmission Electron Microscopy, X-ray photo electron spectroscopy, Zeta potential measurements, UV–Vis spectroscopy, Thermogravimetric Analysis, and Vibrating Sample Magnetometry (VSM). The average particle size was 13 nm. The presence of characteristic functional groups of PVA around the core of magnetite nanoparticles was confirmed by FTIR spectroscopy while the amount of PVA ({\%}) bound to it was estimated by TGA analysis. Zeta potential measurements made by dispersing dilute sonicated samples in a Phosphate Buffer Saline (PBS pH 7.4) confirmed that the particles were negatively charged. The stability and retention of the coating material PVA in PBS (pH7.4) over a period of time were substantiated by UV–Vis spectroscopy. Room-temperature magnetic measurements were made with a VSM which demonstrated the superparamagnetic nature of the particles with higher saturation magnetization of 56.41 emu/g. Furthermore, in vitro cytocompatibility testing of Fe3O4/PVA core–shell composite nanoparticles was carried out on human cervix cancer cells. This confirmed a 97{\%} cell viability with no significant cytotoxicity and thereby substantiated their biocompatibility.",
author = "Rajnish Kurchania and Sawant, {Sachin S.} and Richard Ball",
year = "2014",
month = "10",
day = "15",
doi = "10.1111/jace.13108",
language = "English",
volume = "97",
pages = "3208–3215",
journal = "Journal of the American Ceramic Society",
issn = "0002-7820",
publisher = "Wiley-Blackwell",
number = "10",

}

TY - JOUR

T1 - Synthesis and characterization of magnetite/polyvinyl alcohol core–shell composite nanoparticles

AU - Kurchania, Rajnish

AU - Sawant, Sachin S.

AU - Ball, Richard

PY - 2014/10/15

Y1 - 2014/10/15

N2 - Magnetite (Fe3O4)/polyvinyl alcohol (PVA) core–shell composite nanoparticles were successfully synthesized using a coprecipitation of ferrous and ferric chloride followed by coating with PVA. The resulting nanoparticles were characterized using X-ray diffraction, Fourier Transform Infrared Spectroscopy, Transmission Electron Microscopy, X-ray photo electron spectroscopy, Zeta potential measurements, UV–Vis spectroscopy, Thermogravimetric Analysis, and Vibrating Sample Magnetometry (VSM). The average particle size was 13 nm. The presence of characteristic functional groups of PVA around the core of magnetite nanoparticles was confirmed by FTIR spectroscopy while the amount of PVA (%) bound to it was estimated by TGA analysis. Zeta potential measurements made by dispersing dilute sonicated samples in a Phosphate Buffer Saline (PBS pH 7.4) confirmed that the particles were negatively charged. The stability and retention of the coating material PVA in PBS (pH7.4) over a period of time were substantiated by UV–Vis spectroscopy. Room-temperature magnetic measurements were made with a VSM which demonstrated the superparamagnetic nature of the particles with higher saturation magnetization of 56.41 emu/g. Furthermore, in vitro cytocompatibility testing of Fe3O4/PVA core–shell composite nanoparticles was carried out on human cervix cancer cells. This confirmed a 97% cell viability with no significant cytotoxicity and thereby substantiated their biocompatibility.

AB - Magnetite (Fe3O4)/polyvinyl alcohol (PVA) core–shell composite nanoparticles were successfully synthesized using a coprecipitation of ferrous and ferric chloride followed by coating with PVA. The resulting nanoparticles were characterized using X-ray diffraction, Fourier Transform Infrared Spectroscopy, Transmission Electron Microscopy, X-ray photo electron spectroscopy, Zeta potential measurements, UV–Vis spectroscopy, Thermogravimetric Analysis, and Vibrating Sample Magnetometry (VSM). The average particle size was 13 nm. The presence of characteristic functional groups of PVA around the core of magnetite nanoparticles was confirmed by FTIR spectroscopy while the amount of PVA (%) bound to it was estimated by TGA analysis. Zeta potential measurements made by dispersing dilute sonicated samples in a Phosphate Buffer Saline (PBS pH 7.4) confirmed that the particles were negatively charged. The stability and retention of the coating material PVA in PBS (pH7.4) over a period of time were substantiated by UV–Vis spectroscopy. Room-temperature magnetic measurements were made with a VSM which demonstrated the superparamagnetic nature of the particles with higher saturation magnetization of 56.41 emu/g. Furthermore, in vitro cytocompatibility testing of Fe3O4/PVA core–shell composite nanoparticles was carried out on human cervix cancer cells. This confirmed a 97% cell viability with no significant cytotoxicity and thereby substantiated their biocompatibility.

U2 - 10.1111/jace.13108

DO - 10.1111/jace.13108

M3 - Article

VL - 97

SP - 3208

EP - 3215

JO - Journal of the American Ceramic Society

JF - Journal of the American Ceramic Society

SN - 0002-7820

IS - 10

ER -