Synthesis and biological activity of D-and L-chiro-inositol 2,3,4,5-tetrakisphosphate: design of a novel and potent inhibitor of ins(3,4,5,6)P4 1-kinase/ins(1,3,4)P3 5/6-kinase

Changsheng Liu; Andrew M. Riley; Xiaonian Yang; Stephen B. Shears; Barry V. L. Potter

doi:10.1021/jm000553k

Synthesis and biological activity of D-and L-chiro-inositol 2,3,4,5-tetrakisphosphate: design of a novel and potent inhibitor of ins(3,4,5,6)P₄ 1-kinase/ins(1,3,4)P₃ 5/6-kinase

Changsheng Liu
, Andrew M. Riley
, Xiaonian Yang
, Stephen B. Shears
, Barry V. L. Potter

Department of Life Sciences

Research output: Contribution to journal › Article › peer-review

17 Citations (SciVal)

Original language	English
Pages (from-to)	2984-2989
Journal	Journal of Medicinal Chemistry
Volume	44
Issue number	18
DOIs	https://doi.org/10.1021/jm000553k
Publication status	Published - 2001

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10.1021/jm000553k

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Synthesis and biological activity of D-and L-chiro-inositol 2,3,4,5-tetrakisphosphate: design of a novel and potent inhibitor of ins(3,4,5,6)P₄ 1-kinase/ins(1,3,4)P₃ 5/6-kinase. / Liu, Changsheng; Riley, Andrew M.; Yang, Xiaonian et al.
In: Journal of Medicinal Chemistry, Vol. 44, No. 18, 2001, p. 2984-2989.

Research output: Contribution to journal › Article › peer-review

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title = "Synthesis and biological activity of D-and L-chiro-inositol 2,3,4,5-tetrakisphosphate: design of a novel and potent inhibitor of ins(3,4,5,6)P4 1-kinase/ins(1,3,4)P3 5/6-kinase",

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AU - Liu, Changsheng

AU - Riley, Andrew M.

AU - Yang, Xiaonian

AU - Shears, Stephen B.

AU - Potter, Barry V. L.

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Synthesis and biological activity of D-and L-chiro-inositol 2,3,4,5-tetrakisphosphate: design of a novel and potent inhibitor of ins(3,4,5,6)P4 1-kinase/ins(1,3,4)P3 5/6-kinase

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Synthesis and biological activity of D-and L-chiro-inositol 2,3,4,5-tetrakisphosphate: design of a novel and potent inhibitor of ins(3,4,5,6)P₄ 1-kinase/ins(1,3,4)P₃ 5/6-kinase