Switching stereoselectivity in rhodium-catalysed 1,4-additions

The asymmetric synthesis of 2-substituted pyrrolizidinones

J.D. Hargrave, C.G. Frost, G. Bish

Research output: Contribution to journalArticle

15 Citations (Scopus)

Abstract

The appropriate choice of organometallic nucleophile enables the straightforward preparation of different stereoisomers of 2-substituted pyrrolizidinones utilising the rhodium-catalysed 1,4-addition reaction.
Original languageEnglish
Pages (from-to)4389-4391
Number of pages3
JournalChemical Communications
Volume2006
Issue number42
Early online date2 Oct 2006
DOIs
Publication statusPublished - 2006

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Stereoselectivity
Rhodium
Nucleophiles
Addition reactions
Stereoisomerism
Organometallics

Cite this

Switching stereoselectivity in rhodium-catalysed 1,4-additions : The asymmetric synthesis of 2-substituted pyrrolizidinones. / Hargrave, J.D.; Frost, C.G.; Bish, G.

In: Chemical Communications, Vol. 2006, No. 42, 2006, p. 4389-4391.

Research output: Contribution to journalArticle

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