Switching stereoselectivity in rhodium-catalysed 1,4-additions: The asymmetric synthesis of 2-substituted pyrrolizidinones

J.D. Hargrave; C.G. Frost; G. Bish

doi:10.1039/b610128c

Switching stereoselectivity in rhodium-catalysed 1,4-additions: The asymmetric synthesis of 2-substituted pyrrolizidinones

J.D. Hargrave, C.G. Frost, G. Bish

Pfizer

Research output: Contribution to journal › Article › peer-review

16 Citations (SciVal)

Abstract

The appropriate choice of organometallic nucleophile enables the straightforward preparation of different stereoisomers of 2-substituted pyrrolizidinones utilising the rhodium-catalysed 1,4-addition reaction.

Original language	English
Pages (from-to)	4389-4391
Number of pages	3
Journal	Chemical Communications
Volume	2006
Issue number	42
Early online date	2 Oct 2006
DOIs	https://doi.org/10.1039/b610128c
Publication status	Published - 2006

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10.1039/b610128c

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title = "Switching stereoselectivity in rhodium-catalysed 1,4-additions: The asymmetric synthesis of 2-substituted pyrrolizidinones",

abstract = "The appropriate choice of organometallic nucleophile enables the straightforward preparation of different stereoisomers of 2-substituted pyrrolizidinones utilising the rhodium-catalysed 1,4-addition reaction. ",

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AU - Frost, C.G.

AU - Bish, G.

PY - 2006

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DO - 10.1039/b610128c

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JF - Chemical Communications

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Switching stereoselectivity in rhodium-catalysed 1,4-additions: The asymmetric synthesis of 2-substituted pyrrolizidinones

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HIGH RESOLUTION MASS SPECTROMETERS TO SUPPORT CHEMISTRY AT B ATH

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Switching stereoselectivity in rhodium-catalysed 1,4-additions: The asymmetric synthesis of 2-substituted pyrrolizidinones

Abstract

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HIGH RESOLUTION MASS SPECTROMETERS TO SUPPORT CHEMISTRY AT B ATH

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