Supramolecular aspects of biomolecule interactions in metal–organic frameworks

Christopher Marsh, Greig C. Shearer, Beth T. Knight, Joseph Paul-taylor, Andrew D. Burrows

Research output: Contribution to journalReview articlepeer-review

15 Citations (SciVal)
298 Downloads (Pure)

Abstract

This review focusses on the supramolecular interactions between metal–organic frameworks (MOFs) and included biomolecules. Examples demonstrating the utility of crystallography, spectroscopic techniques, and computational modelling for probing such interactions are highlighted. Key papers illustrating the importance of intraframework interactions to the structure, flexibility, and availability of functional groups in bioMOFs are also discussed. Finally, a range of case studies focussing on applications relating to biosensing, drug delivery, contaminant removal and enzyme immobilisation are discussed as a means of highlighting how the various characterisation techniques can work together to provide an enhanced understanding of the supramolecular chemistry involved and their effects on the application.

Original languageEnglish
Article number213928
JournalCoordination Chemistry Reviews
Volume439
Early online date25 Apr 2021
DOIs
Publication statusPublished - 15 Jul 2021

Bibliographical note

Publisher Copyright:
© 2021 Elsevier B.V.

Funding

The Leverhulme Trust, EPSRC, Wessex Water and the University of Bath are thanked for financial support.

FundersFunder number
Wessex Water Services Ltd
Engineering and Physical Sciences Research Council
Leverhulme Trust

Keywords

  • Biomolecule
  • Metal-organic framework
  • Supramolecular

ASJC Scopus subject areas

  • Physical and Theoretical Chemistry
  • Inorganic Chemistry
  • Materials Chemistry

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