Rapid hydroformylation of 1-octene (rates up to 800 h−1) with the catalyst remaining stable for at least 40 h and with very low rhodium leaching levels (0.5 ppm) is demonstrated when using a system involving flowing the substrate, reacting gases and products dissolved in supercritical CO2 (scCO2) over a fixed bed supported ionic liquid phase catalyst.
Hintermair, U., Zhao, G., Santini, C. C., Muldoon, M. J., & Cole-Hamilton, D. J. (2007). Supported ionic liquid phase catalysis with supercritical flow. Chemical Communications, 2007(14), 1462-1464. https://doi.org/10.1039/b616186c