Abstract
Purpose: To assess the effects of sucrose versus glucose ingestion on post-exercise liver and muscle glycogen repletion. Methods: Fifteen well-trained male cyclists completed 2 test days. Each test day started with glycogen-depleting exercise, followed by 5 h of recovery, during which subjects ingested 1.5 g·kg⁻¹·h⁻¹ sucrose or glucose. Blood was sampled frequently and 13C magnetic resonance spectroscopy and imaging were employed 0, 120, and 300 min post-exercise to determine liver and muscle glycogen concentrations and liver volume. Results: Post-exercise muscle glycogen concentrations increased significantly from 85±27 vs 86±35 mmol·L-1 to 140±23 vs 136±26 mmol·L-1 following sucrose and glucose ingestion, respectively (no differences between treatments: P=0.673). Post-exercise liver glycogen concentrations increased significantly from 183±47 vs 167±65 mmol·L-1 to 280±72 vs 234±81 mmol·L-1 following sucrose and glucose ingestion, respectively (time x treatment, P=0.051). Liver volume increased significantly over the 300 min period after sucrose ingestion only (time x treatment, P=0.001). As a result, total liver glycogen content increased during post-exercise recovery to a greater extent in the sucrose treatment (from 53.6±16.2 to 86.8±29.0 g) compared to the glucose treatment (49.3±25.5 to 65.7±27.1 g; time x treatment, P<0.001), equating to a 3.4 g·h-1 (95%CI: 1.6 to 5.1 g·h-1) greater repletion rate with sucrose vs glucose ingestion. Conclusion: Sucrose ingestion (1.5 g·kg-1·h-1) further accelerates post-exercise liver, but not muscle glycogen repletion when compared to glucose ingestion in trained athletes.This trial was registered at clinicaltrials.gov as NCT02344381.
Original language | English |
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Pages (from-to) | 1328-1334 |
Number of pages | 7 |
Journal | Journal of Applied Physiology |
Volume | 120 |
Issue number | 11 |
Early online date | 24 Mar 2016 |
DOIs | |
Publication status | Published - 1 Jun 2016 |
Keywords
- 13C magnetic resonance spectroscopy
- carbohydrate
- recovery
- fructose
- endurance exercise
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Javier Gonzalez
- Department for Health - Professor
- Centre for Nutrition, Exercise and Metabolism (CNEM)
- Bath Institute for the Augmented Human
Person: Research & Teaching, Affiliate staff