Studies of bimetallic carboxylates: their synthesis, characterization, biological activity and X-ray structure

I Din; M Mazhar; K M Khan; M F Mahon; K C Molloy

doi:10.1016/j.jorganchem.2003.12.019

Studies of bimetallic carboxylates: their synthesis, characterization, biological activity and X-ray structure

I Din, M Mazhar, K M Khan, M F Mahon, K C Molloy

Department of Chemistry

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32 Citations (SciVal)

Abstract

Ten novel diorganotin dicarboxylates containing germanium in the carboxylate ligand have been synthesized and their structures have been characterized by IR, Mossbauer and multinuclear NMR (H-1, C-13, Sn-119) spectroscopies and X-ray diffraction. Also, the twodiastereotopic protons of the methylene group which are directly attached to the chiral center in these compounds have been successfully analyzed for the first time. The resulted ABX system gives three coupling constants and three chemical shifts. The single crystal X-ray analysis of precursor (p-CH3C6H4)(3)GeCH(p-CH3C6H4)CH2COOH revealed the dimeric structure of the molecule through H-bonding between carboxylic acid groups in a conventional manner. The results of their biological activity suggest that the materials have potential to be used as drugs. (C) 2004 Elsevier B.V. All rights reserved.

Original language	English
Pages (from-to)	899-908
Number of pages	10
Journal	Journal of Organometallic Chemistry
Volume	689
Issue number	5
DOIs	https://doi.org/10.1016/j.jorganchem.2003.12.019
Publication status	Published - 2004

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ID number: ISI:000220115800003

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10.1016/j.jorganchem.2003.12.019

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title = "Studies of bimetallic carboxylates: their synthesis, characterization, biological activity and X-ray structure",

abstract = "Ten novel diorganotin dicarboxylates containing germanium in the carboxylate ligand have been synthesized and their structures have been characterized by IR, Mossbauer and multinuclear NMR (H-1, C-13, Sn-119) spectroscopies and X-ray diffraction. Also, the twodiastereotopic protons of the methylene group which are directly attached to the chiral center in these compounds have been successfully analyzed for the first time. The resulted ABX system gives three coupling constants and three chemical shifts. The single crystal X-ray analysis of precursor (p-CH3C6H4)(3)GeCH(p-CH3C6H4)CH2COOH revealed the dimeric structure of the molecule through H-bonding between carboxylic acid groups in a conventional manner. The results of their biological activity suggest that the materials have potential to be used as drugs. (C) 2004 Elsevier B.V. All rights reserved.",

author = "I Din and M Mazhar and Khan, {K M} and Mahon, {M F} and Molloy, {K C}",

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doi = "10.1016/j.jorganchem.2003.12.019",

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journal = "Journal of Organometallic Chemistry",

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T1 - Studies of bimetallic carboxylates: their synthesis, characterization, biological activity and X-ray structure

AU - Din, I

AU - Mazhar, M

AU - Khan, K M

AU - Mahon, M F

AU - Molloy, K C

N1 - ID number: ISI:000220115800003

PY - 2004

Y1 - 2004

N2 - Ten novel diorganotin dicarboxylates containing germanium in the carboxylate ligand have been synthesized and their structures have been characterized by IR, Mossbauer and multinuclear NMR (H-1, C-13, Sn-119) spectroscopies and X-ray diffraction. Also, the twodiastereotopic protons of the methylene group which are directly attached to the chiral center in these compounds have been successfully analyzed for the first time. The resulted ABX system gives three coupling constants and three chemical shifts. The single crystal X-ray analysis of precursor (p-CH3C6H4)(3)GeCH(p-CH3C6H4)CH2COOH revealed the dimeric structure of the molecule through H-bonding between carboxylic acid groups in a conventional manner. The results of their biological activity suggest that the materials have potential to be used as drugs. (C) 2004 Elsevier B.V. All rights reserved.

AB - Ten novel diorganotin dicarboxylates containing germanium in the carboxylate ligand have been synthesized and their structures have been characterized by IR, Mossbauer and multinuclear NMR (H-1, C-13, Sn-119) spectroscopies and X-ray diffraction. Also, the twodiastereotopic protons of the methylene group which are directly attached to the chiral center in these compounds have been successfully analyzed for the first time. The resulted ABX system gives three coupling constants and three chemical shifts. The single crystal X-ray analysis of precursor (p-CH3C6H4)(3)GeCH(p-CH3C6H4)CH2COOH revealed the dimeric structure of the molecule through H-bonding between carboxylic acid groups in a conventional manner. The results of their biological activity suggest that the materials have potential to be used as drugs. (C) 2004 Elsevier B.V. All rights reserved.

U2 - 10.1016/j.jorganchem.2003.12.019

DO - 10.1016/j.jorganchem.2003.12.019

M3 - Article

SN - 0022-328X

VL - 689

SP - 899

EP - 908

JO - Journal of Organometallic Chemistry

JF - Journal of Organometallic Chemistry

IS - 5

ER -

Studies of bimetallic carboxylates: their synthesis, characterization, biological activity and X-ray structure

Abstract

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