Abstract
Herein is reported the production of biodegradable poly (lactic acid) (PLA) and poly (lactic-coglycolic acid) (PLGA) particles having modifiable internal and surface microstructures via single step emulsification using microfabricated 3D (axisymmetric) flow focusing glass capillary microfluidic devices and subsequent solvent evaporation. Controlled production of emulsion droplets was achieved and the morphology of particles produced after evaporation was investigated to ascertain its effect on hydrophobic drug encapsulation and release.
Original language | English |
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Title of host publication | 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 |
Publisher | Chemical and Biological Microsystems Society |
Pages | 971-973 |
Number of pages | 3 |
ISBN (Electronic) | 9780979806476 |
Publication status | Published - 2014 |
Event | 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 - San Antonio, USA United States Duration: 26 Oct 2014 → 30 Oct 2014 |
Conference
Conference | 18th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2014 |
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Country/Territory | USA United States |
City | San Antonio |
Period | 26/10/14 → 30/10/14 |
Keywords
- Biodegradable microparticles
- Drug encapsulation
- Emulsification
- Microfluidic devices
ASJC Scopus subject areas
- Control and Systems Engineering