Structural and biochemical evaluation of the interaction of the phosphatidylinositol 3-kinase p85 ∞ Src homology 2 domains with phosphoinositides and inositol polyphosphates

Paolo Lo Surdo; Matthew J. Bottomley; Alexandre Arcaro; Gregg Siegal; George Panayotou; Andrew Sankar; Piers R. J. Gaffney; Andrew M. Riley; Barry V. L. Potter; Michael D. Waterfield; Paul C. Driscoll

doi:10.1074/jbc.274.22.15678

Structural and biochemical evaluation of the interaction of the phosphatidylinositol 3-kinase p85 ∞ Src homology 2 domains with phosphoinositides and inositol polyphosphates

Paolo Lo Surdo, Matthew J. Bottomley, Alexandre Arcaro, Gregg Siegal, George Panayotou, Andrew Sankar, Piers R. J. Gaffney, Andrew M. Riley, Barry V. L. Potter, Michael D. Waterfield, Paul C. Driscoll

Department of Life Sciences

Research output: Contribution to journal › Article › peer-review

18 Citations (SciVal)

Original language	English
Pages (from-to)	15678-15685
Journal	Journal of Biological Chemistry
Volume	274
Issue number	22
DOIs	https://doi.org/10.1074/jbc.274.22.15678
Publication status	Published - 28 May 1999

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10.1074/jbc.274.22.15678

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Surdo, P. L., Bottomley, M. J., Arcaro, A., Siegal, G., Panayotou, G., Sankar, A., Gaffney, P. R. J., Riley, A. M., Potter, B. V. L., Waterfield, M. D., & Driscoll, P. C. (1999). Structural and biochemical evaluation of the interaction of the phosphatidylinositol 3-kinase p85 ∞ Src homology 2 domains with phosphoinositides and inositol polyphosphates. Journal of Biological Chemistry, 274(22), 15678-15685. https://doi.org/10.1074/jbc.274.22.15678

Structural and biochemical evaluation of the interaction of the phosphatidylinositol 3-kinase p85 ∞ Src homology 2 domains with phosphoinositides and inositol polyphosphates. / Surdo, Paolo Lo; Bottomley, Matthew J.; Arcaro, Alexandre et al.
In: Journal of Biological Chemistry, Vol. 274, No. 22, 28.05.1999, p. 15678-15685.

Research output: Contribution to journal › Article › peer-review

Surdo, PL, Bottomley, MJ, Arcaro, A, Siegal, G, Panayotou, G, Sankar, A, Gaffney, PRJ, Riley, AM, Potter, BVL, Waterfield, MD & Driscoll, PC 1999, 'Structural and biochemical evaluation of the interaction of the phosphatidylinositol 3-kinase p85 ∞ Src homology 2 domains with phosphoinositides and inositol polyphosphates', Journal of Biological Chemistry, vol. 274, no. 22, pp. 15678-15685. https://doi.org/10.1074/jbc.274.22.15678

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title = "Structural and biochemical evaluation of the interaction of the phosphatidylinositol 3-kinase p85 ∞ Src homology 2 domains with phosphoinositides and inositol polyphosphates",

author = "Surdo, \{Paolo Lo\} and Bottomley, \{Matthew J.\} and Alexandre Arcaro and Gregg Siegal and George Panayotou and Andrew Sankar and Gaffney, \{Piers R. J.\} and Riley, \{Andrew M.\} and Potter, \{Barry V. L.\} and Waterfield, \{Michael D.\} and Driscoll, \{Paul C.\}",

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AU - Arcaro, Alexandre

AU - Siegal, Gregg

AU - Panayotou, George

AU - Sankar, Andrew

AU - Gaffney, Piers R. J.

AU - Riley, Andrew M.

AU - Potter, Barry V. L.

AU - Waterfield, Michael D.

AU - Driscoll, Paul C.

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Structural and biochemical evaluation of the interaction of the phosphatidylinositol 3-kinase p85 ∞ Src homology 2 domains with phosphoinositides and inositol polyphosphates

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