@inbook{69d5f06742ef4b6b94b7f4bf034064fe,
title = "Strategies for Multiplexed Electrochemical Sensor Development",
abstract = "Detection of multiple biomarkers for disease diagnosis or treatment monitoring has received a lot of attention due to their potential impact on clinical decision making. Electrochemical biosensors have become one of the preferred detection approaches, due to the simplicity of the accompanying instrumentation. This chapter will explore how electrochemical sensors can be utilized for detection of multiple analytes by integration of sensors into microfluidic microsystems. Some key fabrication technologies for such devices will be presented utilizing polymer microfabrication, paper-based approaches, and the use of printed circuit boards. Next, the use of electrode arrays will be presented along with some commercial platforms, outlining plausible paths towards a successful electrochemical multiplexed sensor. Novel approaches based on microbeads and various labels will then be introduced along with various strategies and technologies utilized to achieve ultrasensitive multiplexed detection.",
keywords = "Electrochemical biosensors, Electrode arrays, Microfluidics integration, Multiplex immunoassays, Printed circuit boards",
author = "Uros Zupancic and Josh Rainbow and Connor Flynn and Josephine Aidoo-Brown and Pedro Estrela and Despina Moschou",
note = "Funding Information: The financial support through the Fundamental Research Grant Scheme (FRGS)-5540309 from Ministry of Education (Malaysia) are appreciatively acknowledged including the support from Universiti Putra Malaysia and Universiti Teknikal Malaysia Melaka. We also wish to express our very sincere thanks to the very competent reviewers for the good comments and suggestions. Funding Information: Acknowledgments: The financial support through the Fundamental Research Grant Scheme (FRGS)–5540309 from Ministry of Education (Malaysia) are appreciatively acknowledged including the support from Universiti Putra Malaysia and Universiti Teknikal Malaysia Melaka. We also wish to express our very sincere thanks to the very competent reviewers for the good comments and suggestions. Publisher Copyright: {\textcopyright} 2021, The Author(s), under exclusive license to Springer Nature Singapore Pte Ltd.",
year = "2021",
month = jan,
day = "5",
doi = "10.1007/978-981-15-9612-4_3",
language = "English",
isbn = "9789811596117",
series = "Studies in Systems, Decision and Control",
publisher = "Springer Nature",
pages = "63--93",
editor = "Gorachand Dutta and Arindam Biswas and Amian Chakrabarti",
booktitle = "Studies in Systems, Decision and Control",
address = "USA United States",
}