Stereoselective synthesis of cyclohexanones via phase transfer catalyzed double addition of nucleophiles to divinyl ketones

Andrew C Silvanus, B J Groombridge, B I Andrews, Gabriele Kociok-Kohn, David R Carbery

Research output: Contribution to journalArticle

25 Citations (Scopus)

Abstract

Functionalized cyclohexanones are formed in excellent yield and diastereoselectivity from a phase transfer catalyzed double addition of active methylene pronucleophiles to non-symmetrical divinyl ketones.
Original languageEnglish
Pages (from-to)7491-7493
Number of pages3
JournalJournal of Organic Chemistry
Volume75
Issue number21
DOIs
Publication statusPublished - 5 Nov 2010

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Cyclohexanones
Nucleophiles
Ketones
1,3-butadiene

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Stereoselective synthesis of cyclohexanones via phase transfer catalyzed double addition of nucleophiles to divinyl ketones. / Silvanus, Andrew C; Groombridge, B J; Andrews, B I; Kociok-Kohn, Gabriele; Carbery, David R.

In: Journal of Organic Chemistry, Vol. 75, No. 21, 05.11.2010, p. 7491-7493.

Research output: Contribution to journalArticle

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