TY - GEN
T1 - SMARTPHONE MULTIPLEX MICROCAPILLARY DIAGNOSTICS USING CYGNUS
T2 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021
AU - Needs, Sarah
AU - Sirivisoot, Sirintra
AU - Jegouic, Sophie
AU - Prommool, Tanapan
AU - Reis, Nuno
AU - Lu-Angaram, Prasit
AU - Srisawat, Chatchawan
AU - Malasit, Prida
AU - Avirutnan, Panisadee
AU - Puttikhunt, Chunya
AU - Edwards, Alexander
N1 - Funding Information:
This study was funded by grants from the Newton Fund (British Council Institutional Links IL35237556) and the Wellcome Trust (Pathfinder Award 204388/Z/16/Z). The clinical cohorts were supported by the Office of the Higher Education Commission, Mahidol University under the National Research Universities Initiative and Research Chair Grant, NSTDA, Thailand. Dumrong Mairiang and Nattaya Tangthawornchaikul (National Science and Technology Development Agency), Adisak Songjaeng, Arunee Mapralub, Supansa Pakdee, Chotika Kaewpuenk, Dararat Prayongkul and Oranicha Khamprapa (Faculty of Medicine Siriraj Hospital, Mahidol University) contributed to dengue hospital cohorts where the collection of dengue clinical specimens and database were used in this study.
PY - 2021/10/14
Y1 - 2021/10/14
N2 - Rapid NS1 tests help dengue diagnosis but cannot identify serotype. A simple,economical, point-of-caredevice for serotyping is still required. We present a gravity driven, smartphone compatible, microfluidic device using microcapillary film (MCF) to perform multiplex serotype-specific detection of dengue virus NS1. A novel device - termed Cygnus - with a stackable design allows analysis of 1 to 12 samples in parallel in 30 minutes using undiluted patient plasma.
AB - Rapid NS1 tests help dengue diagnosis but cannot identify serotype. A simple,economical, point-of-caredevice for serotyping is still required. We present a gravity driven, smartphone compatible, microfluidic device using microcapillary film (MCF) to perform multiplex serotype-specific detection of dengue virus NS1. A novel device - termed Cygnus - with a stackable design allows analysis of 1 to 12 samples in parallel in 30 minutes using undiluted patient plasma.
KW - dengue
KW - diagnostic
KW - fluorescence
KW - infectious disease
KW - smartphone
UR - http://www.scopus.com/inward/record.url?scp=85136929294&partnerID=8YFLogxK
M3 - Chapter in a published conference proceeding
AN - SCOPUS:85136929294
T3 - MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences
SP - 773
EP - 774
BT - MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PB - Chemical and Biological Microsystems Society
Y2 - 10 October 2021 through 14 October 2021
ER -
