SMARTPHONE MULTIPLEX MICROCAPILLARY DIAGNOSTICS USING CYGNUS: AN EVALUATION OF RAPID SEROTYPE-SPECIFIC DENGUE NS1 DETECTION USING 255 PATIENT SAMPLES

Sarah Needs, Sirintra Sirivisoot, Sophie Jegouic, Tanapan Prommool, Nuno Reis, Prasit Lu-Angaram, Chatchawan Srisawat, Prida Malasit, Panisadee Avirutnan, Chunya Puttikhunt, Alexander Edwards

Research output: Chapter or section in a book/report/conference proceedingChapter in a published conference proceeding

Abstract

Rapid NS1 tests help dengue diagnosis but cannot identify serotype. A simple,economical, point-of-caredevice for serotyping is still required. We present a gravity driven, smartphone compatible, microfluidic device using microcapillary film (MCF) to perform multiplex serotype-specific detection of dengue virus NS1. A novel device - termed Cygnus - with a stackable design allows analysis of 1 to 12 samples in parallel in 30 minutes using undiluted patient plasma.

Original languageEnglish
Title of host publicationMicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences
PublisherChemical and Biological Microsystems Society
Pages773-774
Number of pages2
ISBN (Electronic)9781733419031
Publication statusPublished - 14 Oct 2021
Event25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021 - Palm Springs, Virtual, USA United States
Duration: 10 Oct 202114 Oct 2021

Publication series

NameMicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences

Conference

Conference25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021
Country/TerritoryUSA United States
CityPalm Springs, Virtual
Period10/10/2114/10/21

Keywords

  • dengue
  • diagnostic
  • fluorescence
  • infectious disease
  • smartphone

ASJC Scopus subject areas

  • Bioengineering
  • Chemical Engineering (miscellaneous)

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