Abstract
Rapid NS1 tests help dengue diagnosis but cannot identify serotype. A simple,economical, point-of-caredevice for serotyping is still required. We present a gravity driven, smartphone compatible, microfluidic device using microcapillary film (MCF) to perform multiplex serotype-specific detection of dengue virus NS1. A novel device - termed Cygnus - with a stackable design allows analysis of 1 to 12 samples in parallel in 30 minutes using undiluted patient plasma.
| Original language | English |
|---|---|
| Title of host publication | MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences |
| Publisher | Chemical and Biological Microsystems Society |
| Pages | 773-774 |
| Number of pages | 2 |
| ISBN (Electronic) | 9781733419031 |
| Publication status | Published - 14 Oct 2021 |
| Event | 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021 - Palm Springs, Virtual, USA United States Duration: 10 Oct 2021 → 14 Oct 2021 |
Publication series
| Name | MicroTAS 2021 - 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences |
|---|
Conference
| Conference | 25th International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2021 |
|---|---|
| Country/Territory | USA United States |
| City | Palm Springs, Virtual |
| Period | 10/10/21 → 14/10/21 |
Bibliographical note
Funding Information:This study was funded by grants from the Newton Fund (British Council Institutional Links IL35237556) and the Wellcome Trust (Pathfinder Award 204388/Z/16/Z). The clinical cohorts were supported by the Office of the Higher Education Commission, Mahidol University under the National Research Universities Initiative and Research Chair Grant, NSTDA, Thailand. Dumrong Mairiang and Nattaya Tangthawornchaikul (National Science and Technology Development Agency), Adisak Songjaeng, Arunee Mapralub, Supansa Pakdee, Chotika Kaewpuenk, Dararat Prayongkul and Oranicha Khamprapa (Faculty of Medicine Siriraj Hospital, Mahidol University) contributed to dengue hospital cohorts where the collection of dengue clinical specimens and database were used in this study.
Funding
This study was funded by grants from the Newton Fund (British Council Institutional Links IL35237556) and the Wellcome Trust (Pathfinder Award 204388/Z/16/Z). The clinical cohorts were supported by the Office of the Higher Education Commission, Mahidol University under the National Research Universities Initiative and Research Chair Grant, NSTDA, Thailand. Dumrong Mairiang and Nattaya Tangthawornchaikul (National Science and Technology Development Agency), Adisak Songjaeng, Arunee Mapralub, Supansa Pakdee, Chotika Kaewpuenk, Dararat Prayongkul and Oranicha Khamprapa (Faculty of Medicine Siriraj Hospital, Mahidol University) contributed to dengue hospital cohorts where the collection of dengue clinical specimens and database were used in this study.
Keywords
- dengue
- diagnostic
- fluorescence
- infectious disease
- smartphone
ASJC Scopus subject areas
- Bioengineering
- Chemical Engineering (miscellaneous)
