Small molecule antagonists of the σ-1 receptor cause selective release of the death program in tumor and self-reliant cells and inhibit tumor growth  in vitro  and  in vivo

B A Spruce; L A Campbell; N McTavish; M A Cooper; M V L Appleyard; M O'Neill; J Howie; J Samson; S Watt; K Murray; D McLean; N R Leslie; S T Safrany; M J Ferguson; J A Peters; A R Prescott; G Box; A Hayes; B Nutley; F Raynaud; C P Downes; J J Lambert; A M Thompson; S Eccles

Small molecule antagonists of the σ-1 receptor cause selective release of the death program in tumor and self-reliant cells and inhibit tumor growth in vitro and in vivo

B A Spruce
, L A Campbell
, N McTavish
, M A Cooper
, M V L Appleyard
, M O'Neill
, J Howie
, J Samson
, S Watt
, K Murray
, D McLean
, N R Leslie
, S T Safrany
, M J Ferguson
, J A Peters
, A R Prescott
, G Box
, A Hayes
, B Nutley
, F Raynaud

C P Downes, J J Lambert, A M Thompson, S Eccles

Department of Life Sciences

Research output: Contribution to journal › Article › peer-review

166 Citations (SciVal)

Original language	English
Pages (from-to)	4875-4886
Number of pages	12
Journal	Cancer Research
Volume	64
Publication status	Published - 2004

Keywords

in vitro

Cite this

Spruce, B. A., Campbell, L. A., McTavish, N., Cooper, M. A., Appleyard, M. V. L., O'Neill, M., Howie, J., Samson, J., Watt, S., Murray, K., McLean, D., Leslie, N. R., Safrany, S. T., Ferguson, M. J., Peters, J. A., Prescott, A. R., Box, G., Hayes, A., Nutley, B., ... Eccles, S. (2004). Small molecule antagonists of the σ-1 receptor cause selective release of the death program in tumor and self-reliant cells and inhibit tumor growth in vitro and in vivo. Cancer Research, 64, 4875-4886.

Spruce, BA, Campbell, LA, McTavish, N, Cooper, MA, Appleyard, MVL, O'Neill, M, Howie, J, Samson, J, Watt, S, Murray, K, McLean, D, Leslie, NR, Safrany, ST, Ferguson, MJ, Peters, JA, Prescott, AR, Box, G, Hayes, A, Nutley, B, Raynaud, F, Downes, CP, Lambert, JJ, Thompson, AM & Eccles, S 2004, 'Small molecule antagonists of the σ-1 receptor cause selective release of the death program in tumor and self-reliant cells and inhibit tumor growth in vitro and in vivo', Cancer Research, vol. 64, pp. 4875-4886.

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title = "Small molecule antagonists of the σ-1 receptor cause selective release of the death program in tumor and self-reliant cells and inhibit tumor growth in vitro and in vivo",

keywords = "in vitro",

author = "Spruce, \{B A\} and Campbell, \{L A\} and N McTavish and Cooper, \{M A\} and Appleyard, \{M V L\} and M O'Neill and J Howie and J Samson and S Watt and K Murray and D McLean and Leslie, \{N R\} and Safrany, \{S T\} and Ferguson, \{M J\} and Peters, \{J A\} and Prescott, \{A R\} and G Box and A Hayes and B Nutley and F Raynaud and Downes, \{C P\} and Lambert, \{J J\} and Thompson, \{A M\} and S Eccles",

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journal = "Cancer Research",

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T1 - Small molecule antagonists of the σ-1 receptor cause selective release of the death program in tumor and self-reliant cells and inhibit tumor growth in vitro and in vivo

AU - Spruce, B A

AU - Campbell, L A

AU - McTavish, N

AU - Cooper, M A

AU - Appleyard, M V L

AU - O'Neill, M

AU - Howie, J

AU - Samson, J

AU - Watt, S

AU - Murray, K

AU - McLean, D

AU - Leslie, N R

AU - Safrany, S T

AU - Ferguson, M J

AU - Peters, J A

AU - Prescott, A R

AU - Box, G

AU - Hayes, A

AU - Nutley, B

AU - Raynaud, F

AU - Downes, C P

AU - Lambert, J J

AU - Thompson, A M

AU - Eccles, S

PY - 2004

Y1 - 2004

KW - in vitro

M3 - Article

SN - 0008-5472

VL - 64

SP - 4875

EP - 4886

JO - Cancer Research

JF - Cancer Research

ER -