Small molecule antagonists of the σ-1 receptor cause selective release of the death program in tumor and self-reliant cells and inhibit tumor growth in vitro and in vivo

B A Spruce, L A Campbell, N McTavish, M A Cooper, M V L Appleyard, M O'Neill, J Howie, J Samson, S Watt, K Murray, D McLean, N R Leslie, S T Safrany, M J Ferguson, J A Peters, A R Prescott, G Box, A Hayes, B Nutley, F Raynaud & 4 others C P Downes, J J Lambert, A M Thompson, S Eccles

Research output: Contribution to journalArticle

126 Citations (Scopus)
Original languageEnglish
Pages (from-to)4875-4886
Number of pages12
JournalCancer Research
Volume64
Publication statusPublished - 2004

Keywords

  • in vitro

Cite this

Spruce, B. A., Campbell, L. A., McTavish, N., Cooper, M. A., Appleyard, M. V. L., O'Neill, M., ... Eccles, S. (2004). Small molecule antagonists of the σ-1 receptor cause selective release of the death program in tumor and self-reliant cells and inhibit tumor growth in vitro and in vivo. Cancer Research, 64, 4875-4886.

Small molecule antagonists of the σ-1 receptor cause selective release of the death program in tumor and self-reliant cells and inhibit tumor growth in vitro and in vivo. / Spruce, B A; Campbell, L A; McTavish, N; Cooper, M A; Appleyard, M V L; O'Neill, M; Howie, J; Samson, J; Watt, S; Murray, K; McLean, D; Leslie, N R; Safrany, S T; Ferguson, M J; Peters, J A; Prescott, A R; Box, G; Hayes, A; Nutley, B; Raynaud, F; Downes, C P; Lambert, J J; Thompson, A M; Eccles, S.

In: Cancer Research, Vol. 64, 2004, p. 4875-4886.

Research output: Contribution to journalArticle

Spruce, BA, Campbell, LA, McTavish, N, Cooper, MA, Appleyard, MVL, O'Neill, M, Howie, J, Samson, J, Watt, S, Murray, K, McLean, D, Leslie, NR, Safrany, ST, Ferguson, MJ, Peters, JA, Prescott, AR, Box, G, Hayes, A, Nutley, B, Raynaud, F, Downes, CP, Lambert, JJ, Thompson, AM & Eccles, S 2004, 'Small molecule antagonists of the σ-1 receptor cause selective release of the death program in tumor and self-reliant cells and inhibit tumor growth in vitro and in vivo', Cancer Research, vol. 64, pp. 4875-4886.
Spruce, B A ; Campbell, L A ; McTavish, N ; Cooper, M A ; Appleyard, M V L ; O'Neill, M ; Howie, J ; Samson, J ; Watt, S ; Murray, K ; McLean, D ; Leslie, N R ; Safrany, S T ; Ferguson, M J ; Peters, J A ; Prescott, A R ; Box, G ; Hayes, A ; Nutley, B ; Raynaud, F ; Downes, C P ; Lambert, J J ; Thompson, A M ; Eccles, S. / Small molecule antagonists of the σ-1 receptor cause selective release of the death program in tumor and self-reliant cells and inhibit tumor growth in vitro and in vivo. In: Cancer Research. 2004 ; Vol. 64. pp. 4875-4886.
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T1 - Small molecule antagonists of the σ-1 receptor cause selective release of the death program in tumor and self-reliant cells and inhibit tumor growth in vitro and in vivo

AU - Spruce, B A

AU - Campbell, L A

AU - McTavish, N

AU - Cooper, M A

AU - Appleyard, M V L

AU - O'Neill, M

AU - Howie, J

AU - Samson, J

AU - Watt, S

AU - Murray, K

AU - McLean, D

AU - Leslie, N R

AU - Safrany, S T

AU - Ferguson, M J

AU - Peters, J A

AU - Prescott, A R

AU - Box, G

AU - Hayes, A

AU - Nutley, B

AU - Raynaud, F

AU - Downes, C P

AU - Lambert, J J

AU - Thompson, A M

AU - Eccles, S

PY - 2004

Y1 - 2004

KW - in vitro

M3 - Article

VL - 64

SP - 4875

EP - 4886

JO - Cancer Research

JF - Cancer Research

SN - 0008-5472

ER -