Projects per year
Abstract
Objective: The aim of this study was to determine the effects of sustained morning fasting or breakfast consumption on metabolism, energy intake, and appetite in healthy adults with obesity. Methods: An independent-measures randomized controlled trial with baseline and follow-up laboratory assessment days separated by a 6-week intervention of either morning fasting (0 kcal until 12:00 pm) or daily breakfast (> 700 kcal by 11:00 am) was performed. Measures included metabolic outcomes (glucose, insulin, nonesterified fatty acids), hormones regulating appetite (total/acylated ghrelin, peptide YY, leptin), and energy expenditure (diet-induced thermogenesis) parameters throughout a laboratory test day and ad libitum intake following a fixed breakfast. Results: Allocation to fasting versus breakfast resulted in minimal adaptation as reflected by the metabolic outcomes or the majority of appetite regulatory outcomes for either area under curve or time-course-based measures (P > 0.05). Ad libitum lunch intake was not different (P = 0.13), nor was diet-induced thermogenesis or a composite appetite score (both P > 0.10). However, there was a reduced total area under the curve for peptide YY (P = 0.05) and increased postprandial hunger ratings (P = 0.05) in the breakfast group. Conclusions: There was little evidence of metabolic adaptation to acute feeding or negative consequences from sustained morning fasting. This indicates that previously observed differences between breakfast consumers and skippers may be acute effects of feeding or may have resulted from other lifestyle factors.
Original language | English |
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Pages (from-to) | 813-821 |
Number of pages | 9 |
Journal | Obesity |
Volume | 27 |
Issue number | 5 |
Early online date | 29 Mar 2019 |
DOIs | |
Publication status | Published - 1 May 2019 |
Bibliographical note
© 2019 The Authors Obesity published by Wiley Periodicals, Inc. on behalf of The Obesity Society (TOS).Keywords
- Fasting, breakfast, metabolism, energy intake, hormones
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Dive into the research topics of 'Six weeks of morning fasting causes little adaptation of metabolic or appetite responses to feeding in adults with obesity'. Together they form a unique fingerprint.Projects
- 1 Finished
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Extended Daily Fasting (Omission of Breakfast) & the Regulation of Energy Balance
Betts, J. (PI)
Biotechnology and Biological Sciences Research Council
12/04/10 → 10/04/13
Project: Research council
Datasets
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Dataset for "Six weeks of daily morning fasting causes no adaptation of metabolic or appetite responses to feeding in adults with obesity"
Chowdhury, E. (Creator), Betts, J. (Creator), Thompson, D. (Project Member), Gonzalez, J. (Project Member), Richardson, J. (Project Member) & Tsintzas, K. (Project Member), University of Bath, 29 Mar 2019
DOI: 10.15125/BATH-00541
Dataset