Abstract

Cardiac biomarkers have an essential role in diagnosis, risk stratification, clinical and treatment decisions for patients presenting symptoms of e.g. Myocardial Infarction (MI) and Pulmonary Embolism (PE). This paper shows for the first time simultaneous cheap-optical, colourimetric quantitation of cardiac Troponin I (TnI), BNP and D-dimer in whole blood using fluoropolymer microfluidic strips, with a limit of detection (LoD) of 71, 439 and 55 pg/ml, respectively, which compares well with the cut-off values reported for existent commercial-singleplex point-of-care cardiac tests with the advantage of quantitation of multiple biomarkers.

Original languageEnglish
Title of host publication23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
PublisherChemical and Biological Microsystems Society
Pages1588-1589
Number of pages2
ISBN (Electronic)9781733419000
Publication statusPublished - 27 Oct 2019
Event23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019 - Basel, Switzerland
Duration: 27 Oct 201931 Oct 2019

Publication series

Name23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019

Conference

Conference23rd International Conference on Miniaturized Systems for Chemistry and Life Sciences, MicroTAS 2019
CountrySwitzerland
CityBasel
Period27/10/1931/10/19

Keywords

  • BNP
  • Cardiac biomarkers
  • D-dimer
  • Fluoropolymer strips
  • MicroCapillary Film
  • TnI

ASJC Scopus subject areas

  • Bioengineering
  • Chemical Engineering (miscellaneous)

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