Shaping and Reshaping Transcriptome Plasticity During Evolution

Shobbir Hussain

doi:10.1016/j.tibs.2017.06.009

Shaping and Reshaping Transcriptome Plasticity During Evolution

Shobbir Hussain

Department of Life Sciences

Research output: Contribution to journal › Article › peer-review

2 Citations (SciVal)

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Abstract

Transcriptome plasticity, usually associated with alternative isoform generation, is recognised as a key mechanism driving proteomic diversity and biological complexity. Recent findings of Liscovitch-Brauer et al. and Ma et al. suggest that RNA base modifications are an additional central mode of transcriptome malleability that have the potential to determine evolutionary outcomes.

Original language	English
Pages (from-to)	682-684
Journal	Trends in Biochemical Sciences
Volume	42
Issue number	9
Early online date	14 Jul 2017
DOIs	https://doi.org/10.1016/j.tibs.2017.06.009
Publication status	Published - Sep 2017

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10.1016/j.tibs.2017.06.009

Hussain_TiBS spotlight_finalAccepted author manuscript, 26 KBLicence: CC BY-NC-ND

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title = "Shaping and Reshaping Transcriptome Plasticity During Evolution",

abstract = "Transcriptome plasticity, usually associated with alternative isoform generation, is recognised as a key mechanism driving proteomic diversity and biological complexity. Recent findings of Liscovitch-Brauer et al. and Ma et al. suggest that RNA base modifications are an additional central mode of transcriptome malleability that have the potential to determine evolutionary outcomes.",

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year = "2017",

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AB - Transcriptome plasticity, usually associated with alternative isoform generation, is recognised as a key mechanism driving proteomic diversity and biological complexity. Recent findings of Liscovitch-Brauer et al. and Ma et al. suggest that RNA base modifications are an additional central mode of transcriptome malleability that have the potential to determine evolutionary outcomes.

UR - https://doi.org/10.1016/j.tibs.2017.06.009

UR - http://www.cell.com/trends/biochemical-sciences/abstract/S0968-0004(17)30127-5

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JO - Trends in Biochemical Sciences

JF - Trends in Biochemical Sciences

SN - 0968-0004

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Shaping and Reshaping Transcriptome Plasticity During Evolution

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Characterising the Epitanscriptome Using Catalysis-Dependent RIPseq Approaches

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Shaping and Reshaping Transcriptome Plasticity During Evolution

Abstract

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Characterising the Epitanscriptome Using Catalysis-Dependent RIPseq Approaches

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