Serological subsets of juvenile idiopathic inflammatory myopathies - an update

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Abstract

In this review we explore the different characteristics of the serological phenotypes identified in juvenile-onset myositis and consider how the serological sub-classification of patients with juvenile myositis can be advantageous both in terms of reaching what can be a difficult diagnosis and informing on prognosis. Recent studies have described the autoantibody associated disease phenotypes and outcome for those with juvenile-onset disease and include analyses of large juvenile-onset myositis cohorts. Here we describe the autoantibody associated disease features for patients within juvenile-onset myositis in detail and discuss the expanding opportunities and strategies for myositis specific autoantibody testing in clinical practice.

Original languageEnglish
Pages (from-to)427-437
JournalExpert review of clinical immunology
Volume12
Issue number4
Early online date13 Jan 2016
DOIs
Publication statusPublished - 2016

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