Sequential chelation-assisted aromatic C–H functionalisation via catalytic meta sulfonation

William R Reynolds, Po Man Liu, Gabriele Kociok-Kohn, Christopher G Frost

Research output: Contribution to journalLetter

24 Citations (Scopus)

Abstract

The sequential functionalisation of 2-phenylpyridine is presented using selective ortho- and meta-directing processes. It was found that performing a reaction sequence with meta functionalisation first followed by ortho functionalisation provided novel reaction products in good yields and with complete regioselectivity.
Original languageEnglish
Article numberST-2013-D0836-L
Pages (from-to)2687-2690
Number of pages4
JournalSynlett
Volume24
Issue number20
DOIs
Publication statusPublished - 17 Dec 2013

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Regioselectivity
Sulfonation
Chelation
Reaction products
2-phenylpyridine

Cite this

Sequential chelation-assisted aromatic C–H functionalisation via catalytic meta sulfonation. / Reynolds, William R; Liu, Po Man; Kociok-Kohn, Gabriele; Frost, Christopher G.

In: Synlett, Vol. 24, No. 20, ST-2013-D0836-L, 17.12.2013, p. 2687-2690.

Research output: Contribution to journalLetter

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abstract = "The sequential functionalisation of 2-phenylpyridine is presented using selective ortho- and meta-directing processes. It was found that performing a reaction sequence with meta functionalisation first followed by ortho functionalisation provided novel reaction products in good yields and with complete regioselectivity.",
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