Selective preparation of elusive and alternative single component polymorphic solid forms through multi-component crystallisation routes

Lynne H. Thomas, Craig Wales, Chick C. Wilson

Research output: Contribution to journalArticle

12 Citations (Scopus)

Abstract

A transferable, simple, method for producing previously elusive and novel polymorphic forms of important active pharmaceutical ingredients (APIs; paracetamol (acetaminophen), piroxicam and piracetam) is demonstrated. Nitrogen heterocyclic co-molecules are employed to influence the self-assembly crystallisation process in a multi-component environment. Previously unknown solvates have also been synthesised by this method.

Original languageEnglish
Pages (from-to)7372-7375
Number of pages4
JournalChemical Communications
Volume52
Issue number46
DOIs
Publication statusPublished - 11 Jun 2016

Fingerprint Dive into the research topics of 'Selective preparation of elusive and alternative single component polymorphic solid forms through multi-component crystallisation routes'. Together they form a unique fingerprint.

  • Projects

  • Cite this