Scientific, sustainability and regulatory challenges of cultured meat

Mark Post, Shulamit Levenberg, David Kaplan, Nicholas Genovese, Jianan Fu, Chris Bryant, Nicole Negowetti, Karin Verzijden, Panagiota Moutsatsou

Research output: Contribution to journalReview articlepeer-review

228 Citations (SciVal)
2792 Downloads (Pure)


Cellular agriculture is an emerging branch of biotechnology that aims to address issues associated with the environmental impact, animal welfare and sustainability challenges of conventional animal farming for meat production. Cultured meat can be produced by applying current cell culture practices and biomanufacturing methods and utilizing mammalian cell lines and cell and gene therapy products to generate tissue or nutritional proteins for human consumption. However, significant improvements and modifications are needed for the process to be cost efficient and robust enough to be brought to production at scale for food supply. Here, we review the scientific and social challenges in transforming cultured meat into a viable commercial option, covering aspects from cell selection and medium optimization to biomaterials, tissue engineering, regulation and consumer acceptance.
Original languageEnglish
Pages (from-to)403-415
Number of pages13
JournalNature Food
Issue number7
Early online date16 Jul 2020
Publication statusPublished - 31 Jul 2020


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