Scale-up of an RF heated micro trickle bed reactor to a kg/day production scale

Javier Fernández, Sourav Chatterjee, Volkan Degirmenci, Evgeny V. Rebrov

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7 Citations (SciVal)


The scale-up of a radiofrequency (RF) heated micro trickle bed reactor for hydrogenation of 2-methyl-3-butyne-2-ol (MBY) over a Pd/TiO2 catalyst has been performed. The axial and radial temperature profiles were calculated using a 2D convection and conduction heat transfer model. The effect of the reactor length, tube diameter and number of parallel tubes on the temperature non-uniformity parameter has been studied. The axial scale-up was achieved by repeating a single periodic unit consisting of one heating and one catalytic zone along the reactor length. The catalyst loading can be increased by an order of magnitude following this approach. A radial temperature difference of 2 K was developed in a reactor with an inner diameter of 15 mm. The scale-up by numbering up allows the accommodation of seven parallel tubes inside a single RF coil. It creates a 7 K difference in the average temperature between the central and the outer tubes which results in a 5% difference in MBY conversion. An overall scale-up factor of near 700 is achieved which corresponds to a production rate of 0.5 kg of product/day.

Original languageEnglish
Pages (from-to)343-353
Number of pages11
JournalGreen Processing and Synthesis
Issue number5
Publication statusPublished - 1 Sept 2015

Bibliographical note

The financial support provided by the European Research Council (ERC), project 279867, is gratefully acknowledged.


  • fine chemicals
  • magnetic nanoparticles
  • micro reactor
  • radiofrequency
  • scale-up
  • trickle bed

ASJC Scopus subject areas

  • Environmental Chemistry
  • General Chemical Engineering
  • Renewable Energy, Sustainability and the Environment
  • Fuel Technology
  • Industrial and Manufacturing Engineering
  • Health, Toxicology and Mutagenesis


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