Ruthenium xantphos complexes in hydrogen transfer processes: reactivity and mechanistic studies

Araminta E W Ledger, P A Slatford, J P Lowe, Mary F Mahon, Michael K Whittlesey, Jonathan M J Williams

Research output: Contribution to journalArticlepeer-review

46 Citations (Scopus)

Abstract

The in situ combination of [Ru(PPh3)(3)(CO)H-2] with xantphos is catalytically active for the alkylation of alcohols with the ketonitrile (BuC)-Bu-t(O)CH2CN in a model oxidation-Knoevenagel-reduction process. The precursor complex [Ru(xantphos)(PPh3)(CO)H-2] was isolated and reacted with stoichiometric amounts of PhCH2OH and PhCHO. Under these conditions, the alcohol is decarbonylated to afford [Ru(xantphos)(CO)(2)H-2] and finally [Ru(xantphos)(CO)(3)], both of which prove to be less active for catalysis than the starting complex. The reactivity of the xantphos system contrasts with that of [Ru(dppp)(PPh3)(CO)H-2], which is catalytically inactive for the Knoevenagel reaction and fails to show any stoichiometric reactivity with alcohols.
Original languageEnglish
Pages (from-to)716-722
Number of pages7
JournalDalton Transactions
Volume4
DOIs
Publication statusPublished - 2009

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