TY - JOUR
T1 - Ruthenium catalyzed remote C4-selective C–H functionalisation of carbazoles via σ-activation
AU - Leitch, Jamie A.
AU - Heron, Callum J.
AU - Mcknight, Janette
AU - Kociok-Köhn, Gabriele
AU - Bhonoah, Yunas
AU - Frost, Christopher G.
PY - 2017/12/18
Y1 - 2017/12/18
N2 - We report the C4-selective C–H alkylation of carbazole derivatives furnished with a pyrimidine directing group at N9. This was realized using ruthenium catalyzed r-activation methodology, whereby C–H activation at C1 enables the interaction of this ruthenacycle, at the para position to the metal center, with tertiary alkyl radicals
AB - We report the C4-selective C–H alkylation of carbazole derivatives furnished with a pyrimidine directing group at N9. This was realized using ruthenium catalyzed r-activation methodology, whereby C–H activation at C1 enables the interaction of this ruthenacycle, at the para position to the metal center, with tertiary alkyl radicals
UR - http://doi.org/10.1039/C7CC07606A
UR - http://doi.org/10.1039/C7CC07606A
U2 - 10.1039/C7CC07606A
DO - 10.1039/C7CC07606A
M3 - Article
SN - 1359-7345
JO - Chemical Communications
JF - Chemical Communications
ER -