Ruthenium-catalyzed ortho-alkylation of phenols with alcohols by dehydrative coupling

J.W. Walton, Jonathan M J Williams

Research output: Contribution to journalArticle

20 Citations (Scopus)

Abstract

Only water: Phenols have been shown to undergo a ruthenium-catalyzed ortho-alkylation reaction (see scheme; Cy=cyclohexyl). Unactivated alcohols are used as the alkylating agents and water is the only by-product that is generated, making this transformation more atom-economical and greener than traditional methods.
Original languageEnglish
Pages (from-to)12166-12168
Number of pages3
JournalAngewandte Chemie-International Edition
Volume51
Issue number49
DOIs
Publication statusPublished - 3 Dec 2012

Fingerprint

Ruthenium
Phenols
Alkylation
Alcohols
Water
Alkylating Agents

Cite this

Ruthenium-catalyzed ortho-alkylation of phenols with alcohols by dehydrative coupling. / Walton, J.W.; Williams, Jonathan M J.

In: Angewandte Chemie-International Edition, Vol. 51, No. 49, 03.12.2012, p. 12166-12168.

Research output: Contribution to journalArticle

Walton, J.W. ; Williams, Jonathan M J. / Ruthenium-catalyzed ortho-alkylation of phenols with alcohols by dehydrative coupling. In: Angewandte Chemie-International Edition. 2012 ; Vol. 51, No. 49. pp. 12166-12168.
@article{3aac31a8fd51418f8eb2cc4643de5988,
title = "Ruthenium-catalyzed ortho-alkylation of phenols with alcohols by dehydrative coupling",
abstract = "Only water: Phenols have been shown to undergo a ruthenium-catalyzed ortho-alkylation reaction (see scheme; Cy=cyclohexyl). Unactivated alcohols are used as the alkylating agents and water is the only by-product that is generated, making this transformation more atom-economical and greener than traditional methods.",
author = "J.W. Walton and Williams, {Jonathan M J}",
year = "2012",
month = "12",
day = "3",
doi = "10.1002/anie.201206246",
language = "English",
volume = "51",
pages = "12166--12168",
journal = "Angewandte Chemie-International Edition",
issn = "1433-7851",
publisher = "WILEY-V C H VERLAG GMBH",
number = "49",

}

TY - JOUR

T1 - Ruthenium-catalyzed ortho-alkylation of phenols with alcohols by dehydrative coupling

AU - Walton, J.W.

AU - Williams, Jonathan M J

PY - 2012/12/3

Y1 - 2012/12/3

N2 - Only water: Phenols have been shown to undergo a ruthenium-catalyzed ortho-alkylation reaction (see scheme; Cy=cyclohexyl). Unactivated alcohols are used as the alkylating agents and water is the only by-product that is generated, making this transformation more atom-economical and greener than traditional methods.

AB - Only water: Phenols have been shown to undergo a ruthenium-catalyzed ortho-alkylation reaction (see scheme; Cy=cyclohexyl). Unactivated alcohols are used as the alkylating agents and water is the only by-product that is generated, making this transformation more atom-economical and greener than traditional methods.

UR - http://www.scopus.com/inward/record.url?scp=84870514755&partnerID=8YFLogxK

UR - http://dx.doi.org/10.1002/anie.201206246

U2 - 10.1002/anie.201206246

DO - 10.1002/anie.201206246

M3 - Article

VL - 51

SP - 12166

EP - 12168

JO - Angewandte Chemie-International Edition

JF - Angewandte Chemie-International Edition

SN - 1433-7851

IS - 49

ER -