Projects per year
Abstract
A selective catalytic meta sulfonation of 2-phenylpyridines was found to occur in the presence of (arene)ruthenium(II) complexes upon reaction with sulfonyl chlorides. The 2-pyridyl group facilitates the formation of a stable Ru-C(aryl) sigma bond that induces a strong para-directing effect. Electrophilic aromatic substitution proceeds with the sulfonyl chloride to furnish a sulfone at the position meta to the chelating group. This new catalytic process offers access to atypical regioselectivity for reactions involving chelation-assisted cyclometalation.
Original language | English |
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Pages (from-to) | 19298-19301 |
Number of pages | 4 |
Journal | Journal of the American Chemical Society |
Volume | 133 |
Issue number | 48 |
Early online date | 2 Nov 2011 |
DOIs | |
Publication status | Published - 7 Dec 2011 |
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Dive into the research topics of 'Ruthenium-catalyzed meta sulfonation of 2-phenylpyridines'. Together they form a unique fingerprint.Projects
- 2 Finished
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A Flow Process for Aminomethylations using Catalysts Supported on Magnetic Nanoparticles
Frost, C., Plucinski, P. & Price, G.
Engineering and Physical Sciences Research Council
29/06/09 → 28/06/11
Project: Research council
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500 MHZ NMR SPECTROMETER TO SUPPORT ORGANIC, BIO-ORGANIC AND INORGANIC CHEMISTRY
Whittlesey, M., Danson, M., Frost, C., Kohn, R., Lowe, J., Weller, A. & Williams, J.
Engineering and Physical Sciences Research Council
12/06/06 → 11/06/09
Project: Research council