Ruthenium-catalysed conversion of 1,4-alkynediols into pyrroles

S J Pridmore, P A Slatford, A Daniel, M K Whittlesey, J M J Williams

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72 Citations (SciVal)


Various 1,2,5-substituted pyrroles have been synthesised from 1,4-alkynediols using a ruthenium catalysed isomerisation to give the corresponding 1,4-dicarbonyl compounds, which undergo in situ cyclisation to pyrroles in the presence of amine. (C) 2007 Published by Elsevier Ltd.
Original languageEnglish
Pages (from-to)5115-5120
Number of pages6
JournalTetrahedron Letters
Issue number29
Publication statusPublished - 2007


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