Various 1,2,5-substituted pyrroles have been synthesised from 1,4-alkynediols using a ruthenium catalysed isomerisation to give the corresponding 1,4-dicarbonyl compounds, which undergo in situ cyclisation to pyrroles in the presence of amine. (C) 2007 Published by Elsevier Ltd.
Pridmore, S. J., Slatford, P. A., Daniel, A., Whittlesey, M. K., & Williams, J. M. J. (2007). Ruthenium-catalysed conversion of 1,4-alkynediols into pyrroles. Tetrahedron Letters, 48(29), 5115-5120. https://doi.org/10.1016/j.tetlet.2007.05.070