Role of protein concentration on transient film thickness in synovial fluid lubricated joints

Lee Nissim, Hamza Butt, Leiming Gao, Connor Myant, Rob Hewson

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Abstract

A computational model of protein aggregation lubrication has been developed for predicting transient behaviour in lubricated prosthetics. The model uses an advection-diffusion equation to simulate protein transport in order to map concentration changes throughout the contact and inlet zones of an elasto-hydrodynamic contact. Concentration increases lead to exponential increase in fluid viscosity giving rise to lubricating film thicknesses an order of magnitude larger than would be expected using conventional elasto-hydrodynamic theory. The model parameters have been calibrated such that good agreement in transient film thickness is achieved with observed experimental results.
Original languageEnglish
JournalBiotribology
Volume28
Early online date24 Jun 2021
DOIs
Publication statusPublished - 20 Nov 2021

Bibliographical note

Funding
This work was supported by the EPSRC Centre for Doctoral Training in Fluid Dynamics Across Scales [grant number EP/L016230/1].

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