Ribonucleotide Reductase Requires Subunit Switching in Hypoxia to Maintain DNA Replication

Iosifina P. Foskolou; Christian Jorgensen; Katarzyna B. Leszczynska; Monica M. Olcina; Hanna Tarhonskaya; Bauke Haisma; Vincenzo D’Angiolella; William K. Myers; Carmen Domene Nunez; Emily Flashman; Ester M. Hammond

doi:10.1016/j.molcel.2017.03.005

Ribonucleotide Reductase Requires Subunit Switching in Hypoxia to Maintain DNA Replication

Iosifina P. Foskolou, Christian Jorgensen, Katarzyna B. Leszczynska, Monica M. Olcina, Hanna Tarhonskaya, Bauke Haisma, Vincenzo D’Angiolella, William K. Myers, Carmen Domene Nunez, Emily Flashman, Ester M. Hammond

Department of Chemistry

Research output: Contribution to journal › Article › peer-review

76 Citations (SciVal)

Original language	English
Article number	e9
Pages (from-to)	206-220
Journal	Molecular Cell
Volume	66
Issue number	2
DOIs	https://doi.org/10.1016/j.molcel.2017.03.005
Publication status	Published - 1 Apr 2017

Keywords

RNR, RRM2B, replication stress, hypoxia, nucleotides, DNA damage response, radiosensitivity, P53

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10.1016/j.molcel.2017.03.005Licence: CC BY-NC-ND

https://ora.ox.ac.uk/objects/uuid:c87ef1cc-84d5-447d-8eb0-9068fc9040abLicence: CC BY-NC-ND

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@article{334844220c96466dac582af9da319e3e,

title = "Ribonucleotide Reductase Requires Subunit Switching in Hypoxia to Maintain DNA Replication",

keywords = "RNR, RRM2B, replication stress, hypoxia, nucleotides, DNA damage response, radiosensitivity, P53",

author = "Foskolou, \{Iosifina P.\} and Christian Jorgensen and Leszczynska, \{Katarzyna B.\} and Olcina, \{Monica M.\} and Hanna Tarhonskaya and Bauke Haisma and Vincenzo D{\textquoteright}Angiolella and Myers, \{William K.\} and \{Domene Nunez\}, Carmen and Emily Flashman and Hammond, \{Ester M.\}",

year = "2017",

month = apr,

day = "1",

doi = "10.1016/j.molcel.2017.03.005",

language = "English",

volume = "66",

pages = "206--220",

journal = "Molecular Cell",

issn = "1097-2765",

publisher = "Cell Press",

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}

TY - JOUR

T1 - Ribonucleotide Reductase Requires Subunit Switching in Hypoxia to Maintain DNA Replication

AU - Foskolou, Iosifina P.

AU - Jorgensen, Christian

AU - Leszczynska, Katarzyna B.

AU - Olcina, Monica M.

AU - Tarhonskaya, Hanna

AU - Haisma, Bauke

AU - D’Angiolella, Vincenzo

AU - Myers, William K.

AU - Domene Nunez, Carmen

AU - Flashman, Emily

AU - Hammond, Ester M.

PY - 2017/4/1

Y1 - 2017/4/1

KW - RNR, RRM2B, replication stress, hypoxia, nucleotides, DNA damage response, radiosensitivity, P53

UR - http://dx.doi.org/10.1016/j.molcel.2017.03.005

U2 - 10.1016/j.molcel.2017.03.005

DO - 10.1016/j.molcel.2017.03.005

M3 - Article

SN - 1097-2765

VL - 66

SP - 206

EP - 220

JO - Molecular Cell

JF - Molecular Cell

IS - 2

M1 - e9

ER -

Ribonucleotide Reductase Requires Subunit Switching in Hypoxia to Maintain DNA Replication

Keywords

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Carmen Domene

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