TY - JOUR
T1 - Rhodium-catalysed enantioselective synthesis of 4-arylchroman-2-ones
AU - Allen, Joseph C
AU - Kociok-Kohn, Gabriele
AU - Frost, Christopher G
PY - 2012
Y1 - 2012
N2 - The rhodium-catalysed enantioselective 1,4-addition of organoboron reagents to arylidene Meldrum's acids as acceptors, allows convenient access to 4-arylchroman-2-ones with good to excellent levels of enantioselectivity. The use of silyl-protected dioxaborinanes as donors was found to be advantageous to achieving good yields of product under anhydrous conditions.
AB - The rhodium-catalysed enantioselective 1,4-addition of organoboron reagents to arylidene Meldrum's acids as acceptors, allows convenient access to 4-arylchroman-2-ones with good to excellent levels of enantioselectivity. The use of silyl-protected dioxaborinanes as donors was found to be advantageous to achieving good yields of product under anhydrous conditions.
UR - http://www.scopus.com/inward/record.url?scp=82955223244&partnerID=8YFLogxK
UR - http://dx.doi.org/10.1039/c1ob06586f
U2 - 10.1039/c1ob06586f
DO - 10.1039/c1ob06586f
M3 - Article
SN - 1477-0520
VL - 10
SP - 32
EP - 35
JO - Organic and Biomolecular Chemistry
JF - Organic and Biomolecular Chemistry
IS - 1
ER -