Rhodium-catalysed conjugate addition of arylboronic acids to enantiopure dehydroamino acid derivatives

Jonathan D Hargrave, G Bish, Gabriele Kociok-Kohn, Christopher G Frost

Research output: Contribution to journalArticle

5 Citations (Scopus)

Abstract

The rhodium-catalysed conjugate addition of arylboronic acids to an enantiopure acceptor derived from (R)-S-methylcysteine proceeds under substrate control to provide a range of functionalised phenylalanine derivatives with excellent stereocontrol via a highly diastereoselective protonation.
Original languageEnglish
Pages (from-to)5120-5125
Number of pages6
JournalOrganic and Biomolecular Chemistry
Volume8
Issue number22
DOIs
Publication statusPublished - 21 Nov 2010

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