Rhodium-catalysed addition of organotrialkoxysilanes to α-substituted acrylic esters

J.D. Hargrave; J. Herbert; G. Bish; C.G. Frost

doi:10.1039/b606977k

Rhodium-catalysed addition of organotrialkoxysilanes to α-substituted acrylic esters

J.D. Hargrave, J. Herbert, G. Bish, C.G. Frost

Pfizer

Research output: Contribution to journal › Article › peer-review

29 Citations (SciVal)

Abstract

The cationic rhodium complex [Rh(cod)][BF] effectively catalyses the 1,4-addition of organotrialkoxysilanes to α-substituted acrylic esters. The reactions are promoted by heating in an oil-bath or more conveniently in a microwave reactor allowing rapid access to a useful range of functionalised products including 2-alkyl succinates and α-amino acid derivatives.

Original language	English
Pages (from-to)	3235-3241
Number of pages	7
Journal	Organic and Biomolecular Chemistry
Volume	4
Issue number	17
Early online date	25 Jul 2006
DOIs	https://doi.org/10.1039/b606977k
Publication status	Published - 2006

Access to Document

10.1039/b606977k

Cite this

@article{01af4dc8979c43a0bb22022f059b14f0,

title = "Rhodium-catalysed addition of organotrialkoxysilanes to α-substituted acrylic esters",

abstract = "The cationic rhodium complex [Rh(cod)][BF] effectively catalyses the 1,4-addition of organotrialkoxysilanes to α-substituted acrylic esters. The reactions are promoted by heating in an oil-bath or more conveniently in a microwave reactor allowing rapid access to a useful range of functionalised products including 2-alkyl succinates and α-amino acid derivatives. ",

author = "J.D. Hargrave and J. Herbert and G. Bish and C.G. Frost",

year = "2006",

doi = "10.1039/b606977k",

language = "English",

volume = "4",

pages = "3235--3241",

journal = "Organic and Biomolecular Chemistry",

issn = "1477-0520",

publisher = "Royal Society of Chemistry",

number = "17",

}

TY - JOUR

T1 - Rhodium-catalysed addition of organotrialkoxysilanes to α-substituted acrylic esters

AU - Hargrave, J.D.

AU - Herbert, J.

AU - Bish, G.

AU - Frost, C.G.

PY - 2006

Y1 - 2006

N2 - The cationic rhodium complex [Rh(cod)][BF] effectively catalyses the 1,4-addition of organotrialkoxysilanes to α-substituted acrylic esters. The reactions are promoted by heating in an oil-bath or more conveniently in a microwave reactor allowing rapid access to a useful range of functionalised products including 2-alkyl succinates and α-amino acid derivatives.

AB - The cationic rhodium complex [Rh(cod)][BF] effectively catalyses the 1,4-addition of organotrialkoxysilanes to α-substituted acrylic esters. The reactions are promoted by heating in an oil-bath or more conveniently in a microwave reactor allowing rapid access to a useful range of functionalised products including 2-alkyl succinates and α-amino acid derivatives.

UR - https://www.scopus.com/pages/publications/33747888984

UR - http://dx.doi.org/10.1039/b606977k

U2 - 10.1039/b606977k

DO - 10.1039/b606977k

M3 - Article

AN - SCOPUS:33747888984

SN - 1477-0520

VL - 4

SP - 3235

EP - 3241

JO - Organic and Biomolecular Chemistry

JF - Organic and Biomolecular Chemistry

IS - 17

ER -

Rhodium-catalysed addition of organotrialkoxysilanes to α-substituted acrylic esters

Abstract

Access to Document

Other files and links

Fingerprint

Cite this