Rhodium-catalysed addition of organotrialkoxysilanes to α-substituted acrylic esters

J.D. Hargrave; J. Herbert; G. Bish; C.G. Frost

doi:10.1039/b606977k

Rhodium-catalysed addition of organotrialkoxysilanes to α-substituted acrylic esters

J.D. Hargrave, J. Herbert, G. Bish, C.G. Frost

Pfizer

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29 Citations (SciVal)

Abstract

The cationic rhodium complex [Rh(cod)][BF] effectively catalyses the 1,4-addition of organotrialkoxysilanes to α-substituted acrylic esters. The reactions are promoted by heating in an oil-bath or more conveniently in a microwave reactor allowing rapid access to a useful range of functionalised products including 2-alkyl succinates and α-amino acid derivatives.

Original language	English
Pages (from-to)	3235-3241
Number of pages	7
Journal	Organic and Biomolecular Chemistry
Volume	4
Issue number	17
Early online date	25 Jul 2006
DOIs	https://doi.org/10.1039/b606977k
Publication status	Published - 2006

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title = "Rhodium-catalysed addition of organotrialkoxysilanes to α-substituted acrylic esters",

abstract = "The cationic rhodium complex [Rh(cod)][BF] effectively catalyses the 1,4-addition of organotrialkoxysilanes to α-substituted acrylic esters. The reactions are promoted by heating in an oil-bath or more conveniently in a microwave reactor allowing rapid access to a useful range of functionalised products including 2-alkyl succinates and α-amino acid derivatives. ",

author = "J.D. Hargrave and J. Herbert and G. Bish and C.G. Frost",

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AU - Hargrave, J.D.

AU - Herbert, J.

AU - Bish, G.

AU - Frost, C.G.

PY - 2006

Y1 - 2006

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AB - The cationic rhodium complex [Rh(cod)][BF] effectively catalyses the 1,4-addition of organotrialkoxysilanes to α-substituted acrylic esters. The reactions are promoted by heating in an oil-bath or more conveniently in a microwave reactor allowing rapid access to a useful range of functionalised products including 2-alkyl succinates and α-amino acid derivatives.

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DO - 10.1039/b606977k

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AN - SCOPUS:33747888984

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ER -

Rhodium-catalysed addition of organotrialkoxysilanes to α-substituted acrylic esters

Abstract

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