Regio- and stereoselective functionalisation of monocyclic medium ring lactams

P. Andrew Evans; Ian Collins; Peter Hamley; Andrew B. Holmes; Paul R. Raithby; Keith Russell

doi:10.1016/S0040-4039(00)61795-1

Regio- and stereoselective functionalisation of monocyclic medium ring lactams

P. Andrew Evans, Ian Collins, Peter Hamley, Andrew B. Holmes, Paul R. Raithby, Keith Russell

Research output: Contribution to journal › Article › peer-review

Abstract

The functionalisation of the potassium enolates of a series of racemic 7-, 8-, and 9-membered unsaturated lactams with trisyl azide and phenylselenenyl chloride afforded the corresponding 3,n-disubstituted lactams with good stereoselectivities.

Original language	English
Pages (from-to)	6859-6862
Number of pages	4
Journal	Tetrahedron Letters
Volume	33
Issue number	45
DOIs	https://doi.org/10.1016/S0040-4039(00)61795-1
Publication status	Published - 3 Nov 1992

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(00)61795-1

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@article{ca7d17ed37af4cd08f260201773792e9,

title = "Regio- and stereoselective functionalisation of monocyclic medium ring lactams",

abstract = "The functionalisation of the potassium enolates of a series of racemic 7-, 8-, and 9-membered unsaturated lactams with trisyl azide and phenylselenenyl chloride afforded the corresponding 3,n-disubstituted lactams with good stereoselectivities.",

author = "{Andrew Evans}, P. and Ian Collins and Peter Hamley and Holmes, {Andrew B.} and Raithby, {Paul R.} and Keith Russell",

year = "1992",

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doi = "10.1016/S0040-4039(00)61795-1",

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T1 - Regio- and stereoselective functionalisation of monocyclic medium ring lactams

AU - Andrew Evans, P.

AU - Collins, Ian

AU - Hamley, Peter

AU - Holmes, Andrew B.

AU - Raithby, Paul R.

AU - Russell, Keith

PY - 1992/11/3

Y1 - 1992/11/3

N2 - The functionalisation of the potassium enolates of a series of racemic 7-, 8-, and 9-membered unsaturated lactams with trisyl azide and phenylselenenyl chloride afforded the corresponding 3,n-disubstituted lactams with good stereoselectivities.

AB - The functionalisation of the potassium enolates of a series of racemic 7-, 8-, and 9-membered unsaturated lactams with trisyl azide and phenylselenenyl chloride afforded the corresponding 3,n-disubstituted lactams with good stereoselectivities.

UR - http://www.scopus.com/inward/record.url?scp=0026492646&partnerID=8YFLogxK

U2 - 10.1016/S0040-4039(00)61795-1

DO - 10.1016/S0040-4039(00)61795-1

M3 - Article

AN - SCOPUS:0026492646

SN - 0040-4039

VL - 33

SP - 6859

EP - 6862

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 45

ER -

Regio- and stereoselective functionalisation of monocyclic medium ring lactams

Abstract

ASJC Scopus subject areas

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