Regeneration behavior of chitosan from ionic liquid using water and alcohols as anti-solvents

Xiaoyan Tan; Guowei Wang; Lei Zhong; Fengwei Xie; Ping Lan; Bo Chi

doi:10.1016/j.ijbiomac.2020.10.251

Regeneration behavior of chitosan from ionic liquid using water and alcohols as anti-solvents

Xiaoyan Tan
, Guowei Wang
, Lei Zhong
, Fengwei Xie
, Ping Lan
, Bo Chi

Nanjing Tech University
Guangxi University for Nationalities
University of Warwick

Research output: Contribution to journal › Article › peer-review

17 Citations (SciVal)

Abstract

While ionic liquids (ILs) have been considered as effective and “green” solvents for biopolymer processing, regeneration of IL-dissolved biopolymers could largely impact biopolymer structure and properties. This study indicates that the reconstitution of chitosan structure during regeneration from 1-ethyl-3-methylimidazolium acetate ([Emim][OAc]) depends on anti-solvent (water, methanol or ethanol) largely. Irrespective of anti-solvent, the chitosan chemical structure was not varied by dissolution or regeneration. With water, the regenerated chitosan had the highest crystallinity index of 54.18%, followed by those with methanol (35.07%) and ethanol (25.65%). Water as an anti-solvent could promote chitosan chain rearrangement, leading to the formation of an ordered aggregated structure and crystallites. Density functional theory (DFT) simulation indicates that the number of hydrogen bonds formed between anti-solvents and [Emim][OAc] was in the order of water > methanol > ethanol. With water used for regeneration, the aggregation and rearrangement of chitosan chains occurred more easily.

Original language	English
Pages (from-to)	940-947
Number of pages	8
Journal	International Journal of Biological Macromolecules
Volume	166
Early online date	2 Nov 2020
DOIs	https://doi.org/10.1016/j.ijbiomac.2020.10.251
Publication status	Published - 1 Jan 2021

Bibliographical note

Publisher Copyright:
© 2020 Elsevier B.V.

Funding

The authors would like to acknowledge the Natural Science Foundation of Jiangsu Province , the National Natural Science Foundation of China (grant No. 31771049 ), the Key Research and Development Project of Jiangsu Province (grant No. BE2018731 ), and the Research Foundation of the State Key Laboratory of Materials- Oriented Chemical Engineering (grant No. ZK201806 ). This work is also supported by Guangxi Key Laboratory for Polysaccharide Materials and Modification, Guangxi University for Nationalities (grant No. GXPSMM18ZD-04 ), and Nanjing Tech University Research Start-up Grants for Introduced Talents. The authors would like to acknowledge the Natural Science Foundation of Jiangsu Province, the National Natural Science Foundation of China (grant No. 31771049), the Key Research and Development Project of Jiangsu Province (grant No. BE2018731), and the Research Foundation of the State Key Laboratory of Materials- Oriented Chemical Engineering (grant No. ZK201806). This work is also supported by Guangxi Key Laboratory for Polysaccharide Materials and Modification, Guangxi University for Nationalities (grant No. GXPSMM18ZD-04), and Nanjing Tech University Research Start-up Grants for Introduced Talents.

Funders	Funder number
Guangxi Key Laboratory for Polysaccharide Materials and Modification
Nanjing Tech University Research Start-up Grants for Introduced Talents
Research Foundation of the State Key Laboratory of Materials- Oriented Chemical Engineering
National Natural Science Foundation of China	31771049
Natural Science Foundation of Jiangsu Province
Guangxi University for Nationalities	GXPSMM18ZD-04
State Key Laboratory of Materials-Oriented Chemical Engineering	ZK201806
Jiangsu Provincial Key Research and Development Program	BE2018731

Keywords

1-Ethyl-3-methylimidazolium acetate
Anti-solvent
Chitosan regeneration
Density functional theory
Ionic liquid
Molecular simulation

ASJC Scopus subject areas

Structural Biology
Biochemistry
Molecular Biology
Economics and Econometrics
General Energy

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10.1016/j.ijbiomac.2020.10.251

Cite this

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title = "Regeneration behavior of chitosan from ionic liquid using water and alcohols as anti-solvents",

abstract = "While ionic liquids (ILs) have been considered as effective and “green” solvents for biopolymer processing, regeneration of IL-dissolved biopolymers could largely impact biopolymer structure and properties. This study indicates that the reconstitution of chitosan structure during regeneration from 1-ethyl-3-methylimidazolium acetate ([Emim][OAc]) depends on anti-solvent (water, methanol or ethanol) largely. Irrespective of anti-solvent, the chitosan chemical structure was not varied by dissolution or regeneration. With water, the regenerated chitosan had the highest crystallinity index of 54.18\%, followed by those with methanol (35.07\%) and ethanol (25.65\%). Water as an anti-solvent could promote chitosan chain rearrangement, leading to the formation of an ordered aggregated structure and crystallites. Density functional theory (DFT) simulation indicates that the number of hydrogen bonds formed between anti-solvents and [Emim][OAc] was in the order of water > methanol > ethanol. With water used for regeneration, the aggregation and rearrangement of chitosan chains occurred more easily.",

keywords = "1-Ethyl-3-methylimidazolium acetate, Anti-solvent, Chitosan regeneration, Density functional theory, Ionic liquid, Molecular simulation",

author = "Xiaoyan Tan and Guowei Wang and Lei Zhong and Fengwei Xie and Ping Lan and Bo Chi",

note = "Publisher Copyright: {\textcopyright} 2020 Elsevier B.V.",

year = "2021",

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day = "1",

doi = "10.1016/j.ijbiomac.2020.10.251",

language = "English",

volume = "166",

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AU - Tan, Xiaoyan

AU - Wang, Guowei

AU - Zhong, Lei

AU - Xie, Fengwei

AU - Lan, Ping

AU - Chi, Bo

PY - 2021/1/1

Y1 - 2021/1/1

N2 - While ionic liquids (ILs) have been considered as effective and “green” solvents for biopolymer processing, regeneration of IL-dissolved biopolymers could largely impact biopolymer structure and properties. This study indicates that the reconstitution of chitosan structure during regeneration from 1-ethyl-3-methylimidazolium acetate ([Emim][OAc]) depends on anti-solvent (water, methanol or ethanol) largely. Irrespective of anti-solvent, the chitosan chemical structure was not varied by dissolution or regeneration. With water, the regenerated chitosan had the highest crystallinity index of 54.18%, followed by those with methanol (35.07%) and ethanol (25.65%). Water as an anti-solvent could promote chitosan chain rearrangement, leading to the formation of an ordered aggregated structure and crystallites. Density functional theory (DFT) simulation indicates that the number of hydrogen bonds formed between anti-solvents and [Emim][OAc] was in the order of water > methanol > ethanol. With water used for regeneration, the aggregation and rearrangement of chitosan chains occurred more easily.

AB - While ionic liquids (ILs) have been considered as effective and “green” solvents for biopolymer processing, regeneration of IL-dissolved biopolymers could largely impact biopolymer structure and properties. This study indicates that the reconstitution of chitosan structure during regeneration from 1-ethyl-3-methylimidazolium acetate ([Emim][OAc]) depends on anti-solvent (water, methanol or ethanol) largely. Irrespective of anti-solvent, the chitosan chemical structure was not varied by dissolution or regeneration. With water, the regenerated chitosan had the highest crystallinity index of 54.18%, followed by those with methanol (35.07%) and ethanol (25.65%). Water as an anti-solvent could promote chitosan chain rearrangement, leading to the formation of an ordered aggregated structure and crystallites. Density functional theory (DFT) simulation indicates that the number of hydrogen bonds formed between anti-solvents and [Emim][OAc] was in the order of water > methanol > ethanol. With water used for regeneration, the aggregation and rearrangement of chitosan chains occurred more easily.

KW - 1-Ethyl-3-methylimidazolium acetate

KW - Anti-solvent

KW - Chitosan regeneration

KW - Density functional theory

KW - Ionic liquid

KW - Molecular simulation

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JO - International Journal of Biological Macromolecules

JF - International Journal of Biological Macromolecules

ER -

Regeneration behavior of chitosan from ionic liquid using water and alcohols as anti-solvents

Abstract

Bibliographical note

Funding

Keywords

ASJC Scopus subject areas

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