Abstract
SUMMARY: Homologous recombination is an important evolutionary process in bacteria and other prokaryotes, which increases genomic sequence diversity and can facilitate adaptation. Several methods and tools have been developed to detect genomic regions recently affected by recombination. Exploration and visualization of such recombination events can reveal valuable biological insights, but it remains challenging. Here, we present RCandy, a platform-independent R package for rapid, simple and flexible visualization of recombination events in bacterial genomes.
AVAILABILITY AND IMPLEMENTATION: RCandy is an R package freely available for use under the MIT license. It is platform-independent and has been tested on Windows, Linux and MacOSX. The source code comes together with a detailed vignette available on GitHub at https://github.com/ChrispinChaguza/RCandy.
SUPPLEMENTARY INFORMATION: Supplementary data are available at Bioinformatics online.
Original language | English |
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Pages (from-to) | 1450-1451 |
Number of pages | 2 |
Journal | Bioinformatics |
Volume | 38 |
Issue number | 5 |
Early online date | 2 Dec 2021 |
DOIs | |
Publication status | Published - 1 Mar 2022 |
Bibliographical note
FundingThis work was supported by the Joint Initiative for Antimicrobial Resistance [MR/R003076/1]; the Bill and Melinda Gates Foundation [OPP1034556]; and Wellcome Trust [2016-2021 core award Grant 206194].
Data availability
All data are incorporated into the article and its online supplementary material.
Keywords
- Genomics
- Software
- Genome
- Bacteria
- Biological Evolution