Ratiometric two-photon fluorescent probe for

In situ imaging of carboxylesterase (CE)-mediated mitochondrial acidification during medication

Ao Jiang, Guang Chen, Jie Xu, Yuxia Liu, Guanghui Zhao, Zhenjun Liu, Tao Chen, Yulin Li, Tony D. James

Research output: Contribution to journalArticle

4 Citations (Scopus)

Abstract

We report on a dual ratiometric two-photon fluorescent probe for in situ sensing of mitochondrial CE activity and pH. Using the probe it is possible to visualize the CE-mediated acidification of hepatoma cells and hepatic tissues during medication with antipyretic anti-inflammatory drugs.

Original languageEnglish
Pages (from-to)11358-11361
Number of pages4
JournalChemical Communications
Volume55
Issue number76
Early online date3 Sep 2019
DOIs
Publication statusPublished - 28 Sep 2019

ASJC Scopus subject areas

  • Catalysis
  • Electronic, Optical and Magnetic Materials
  • Ceramics and Composites
  • Chemistry(all)
  • Surfaces, Coatings and Films
  • Metals and Alloys
  • Materials Chemistry

Cite this

Ratiometric two-photon fluorescent probe for : In situ imaging of carboxylesterase (CE)-mediated mitochondrial acidification during medication. / Jiang, Ao; Chen, Guang; Xu, Jie; Liu, Yuxia; Zhao, Guanghui; Liu, Zhenjun; Chen, Tao; Li, Yulin; James, Tony D.

In: Chemical Communications, Vol. 55, No. 76, 28.09.2019, p. 11358-11361.

Research output: Contribution to journalArticle

Jiang, Ao ; Chen, Guang ; Xu, Jie ; Liu, Yuxia ; Zhao, Guanghui ; Liu, Zhenjun ; Chen, Tao ; Li, Yulin ; James, Tony D. / Ratiometric two-photon fluorescent probe for : In situ imaging of carboxylesterase (CE)-mediated mitochondrial acidification during medication. In: Chemical Communications. 2019 ; Vol. 55, No. 76. pp. 11358-11361.
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AU - Liu, Zhenjun

AU - Chen, Tao

AU - Li, Yulin

AU - James, Tony D.

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