Abstract
We report on a dual ratiometric two-photon fluorescent probe for in situ sensing of mitochondrial CE activity and pH. Using the probe it is possible to visualize the CE-mediated acidification of hepatoma cells and hepatic tissues during medication with antipyretic anti-inflammatory drugs.
| Original language | English |
|---|---|
| Pages (from-to) | 11358-11361 |
| Number of pages | 4 |
| Journal | Chemical Communications |
| Volume | 55 |
| Issue number | 76 |
| Early online date | 3 Sep 2019 |
| DOIs | |
| Publication status | Published - 28 Sep 2019 |
ASJC Scopus subject areas
- Catalysis
- Electronic, Optical and Magnetic Materials
- Ceramics and Composites
- Chemistry(all)
- Surfaces, Coatings and Films
- Metals and Alloys
- Materials Chemistry
Cite this
Jiang, A., Chen, G., Xu, J., Liu, Y., Zhao, G., Liu, Z., Chen, T., Li, Y., & James, T. D. (2019). Ratiometric two-photon fluorescent probe for: In situ imaging of carboxylesterase (CE)-mediated mitochondrial acidification during medication. Chemical Communications, 55(76), 11358-11361. https://doi.org/10.1039/c9cc05759e