Abstract
We report on a dual ratiometric two-photon fluorescent probe for in situ sensing of mitochondrial CE activity and pH. Using the probe it is possible to visualize the CE-mediated acidification of hepatoma cells and hepatic tissues during medication with antipyretic anti-inflammatory drugs.
Original language | English |
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Pages (from-to) | 11358-11361 |
Number of pages | 4 |
Journal | Chemical Communications |
Volume | 55 |
Issue number | 76 |
Early online date | 3 Sept 2019 |
DOIs | |
Publication status | Published - 28 Sept 2019 |
Funding
This work was supported by National Natural Science Foundation of China (No. 21475074, and 21403123), the China Postdoctoral Science Foundation (2017M622254; 2016M600531), the Open Funds of the Shandong Province Key Laboratory of Detection Technology for Tumor Markers (KLDTTM2015-6; KLDTTM2015-9), and the Natural Science Foundation of Shan-dong Province (ZR201709240033). T. D. J. thanks the Royal Society for a Wolfson Research Merit Award.
ASJC Scopus subject areas
- Catalysis
- Electronic, Optical and Magnetic Materials
- Ceramics and Composites
- General Chemistry
- Surfaces, Coatings and Films
- Metals and Alloys
- Materials Chemistry