Abstract
We report on a dual ratiometric two-photon fluorescent probe for in situ sensing of mitochondrial CE activity and pH. Using the probe it is possible to visualize the CE-mediated acidification of hepatoma cells and hepatic tissues during medication with antipyretic anti-inflammatory drugs.
| Original language | English |
|---|---|
| Pages (from-to) | 11358-11361 |
| Number of pages | 4 |
| Journal | Chemical Communications |
| Volume | 55 |
| Issue number | 76 |
| Early online date | 3 Sep 2019 |
| DOIs | |
| Publication status | Published - 28 Sep 2019 |
ASJC Scopus subject areas
- Catalysis
- Electronic, Optical and Magnetic Materials
- Ceramics and Composites
- Chemistry(all)
- Surfaces, Coatings and Films
- Metals and Alloys
- Materials Chemistry
Cite this
Ratiometric two-photon fluorescent probe for : In situ imaging of carboxylesterase (CE)-mediated mitochondrial acidification during medication. / Jiang, Ao; Chen, Guang; Xu, Jie; Liu, Yuxia; Zhao, Guanghui; Liu, Zhenjun; Chen, Tao; Li, Yulin; James, Tony D.
In: Chemical Communications, Vol. 55, No. 76, 28.09.2019, p. 11358-11361.Research output: Contribution to journal › Article
}
TY - JOUR
T1 - Ratiometric two-photon fluorescent probe for
T2 - In situ imaging of carboxylesterase (CE)-mediated mitochondrial acidification during medication
AU - Jiang, Ao
AU - Chen, Guang
AU - Xu, Jie
AU - Liu, Yuxia
AU - Zhao, Guanghui
AU - Liu, Zhenjun
AU - Chen, Tao
AU - Li, Yulin
AU - James, Tony D.
PY - 2019/9/28
Y1 - 2019/9/28
N2 - We report on a dual ratiometric two-photon fluorescent probe for in situ sensing of mitochondrial CE activity and pH. Using the probe it is possible to visualize the CE-mediated acidification of hepatoma cells and hepatic tissues during medication with antipyretic anti-inflammatory drugs.
AB - We report on a dual ratiometric two-photon fluorescent probe for in situ sensing of mitochondrial CE activity and pH. Using the probe it is possible to visualize the CE-mediated acidification of hepatoma cells and hepatic tissues during medication with antipyretic anti-inflammatory drugs.
UR - http://www.scopus.com/inward/record.url?scp=85072509628&partnerID=8YFLogxK
U2 - 10.1039/c9cc05759e
DO - 10.1039/c9cc05759e
M3 - Article
VL - 55
SP - 11358
EP - 11361
JO - Chemical communications (Cambridge, England)
JF - Chemical communications (Cambridge, England)
SN - 1359-7345
IS - 76
ER -