Rapid selection for ivermectin resistance in Haemonchus contortus

G C Coles, A C Rhodes, A Wolstenholme

Research output: Contribution to journalArticle

39 Citations (Scopus)

Abstract

Lambs infected with two isolates, one British and one American, of Haemonchus contortus were treated with increasing doses of ivermectin. Eggs from the highest dose that had not eliminated the infection were cultured and larvae used to infect another lamb. After three generations the H. contortus was resistant to 0.2 mg/kg ivermectin. The results stress the ease with which ivermectin resistance can be selected if high selection pressure is applied. (c) 2005 Elsevier B.V. All rights reserved.
Original languageEnglish
Pages (from-to)345-347
Number of pages3
JournalVeterinary Parasitology
Volume129
Issue number3-4
DOIs
Publication statusPublished - 2005

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