Rapid detection of synthetic cannabinoids via fluorescence spectral fingerprints

R. Kumar; Gyles E. Cozier; Rachael C. Andrews; Christopher R. Pudney

doi:10.1117/12.2685133

Rapid detection of synthetic cannabinoids via fluorescence spectral fingerprints

R. Kumar, Gyles E. Cozier, Rachael C. Andrews, Christopher R. Pudney

Research output: Chapter or section in a book/report/conference proceeding › Chapter in a published conference proceeding

Abstract

Synthetic Cannabinoids (SCs), also known as "Spice", are a category of Schedule 1 drugs consisting of over 200 chemically diverse compounds. They are prevalent in UK prisons and homeless groups often sold on a range of matrices (herbal, paper and fabric) and at unknown concentrations. To reduce the harm these drugs cause, rapid and accurate detection is required. Due to their chemical diversity, detection can be challenging. Their identification can be achieved using spectroscopic approaches such as LCQTOF-MS, LC-MS-MS, GC-MS, NMR, and ATR-IR. However, these are time-consuming and laboratory-intensive, requiring advanced training. Recently, we provided evidence that excitationemission matrices can be used to 'fingerprint the presence of SCs' which we call a fluorescence spectral fingerprint (FSF). Here we demonstrate a portable device, based-on an array of LEDs as excitation sources, that can produce FSFs that are of sufficiently high resolution to discriminate FSFs of individual SCs.

Original language	English
Title of host publication	UV and Higher Energy Photonics
Subtitle of host publication	From Materials to Applications 2023
Editors	Gilles Lerondel, Yong-Hoon Cho, Atsushi Taguchi, Satoshi Kawata
Place of Publication	U. S. A.
Publisher	SPIE
ISBN (Electronic)	9781510665187
DOIs	https://doi.org/10.1117/12.2685133
Publication status	Published - 5 Oct 2023
Event	UV and Higher Energy Photonics: From Materials to Applications 2023 - San Diego, USA United States Duration: 20 Aug 2023 → 21 Aug 2023

Publication series

Name	Proceedings of SPIE - The International Society for Optical Engineering
Volume	12652
ISSN (Print)	0277-786X
ISSN (Electronic)	1996-756X

Conference

Conference	UV and Higher Energy Photonics: From Materials to Applications 2023
Country/Territory	USA United States
City	San Diego
Period	20/08/23 → 21/08/23

Bibliographical note

.

Funding

The authors acknowledge the UKRI for funding (EP/V026917/1) the current project. Material in the manuscript is relevant to U.K. patent application number 2219561.4.

Keywords

Fluorescence spectral fingerprint (FSF)
Forensic Science
Novel Psychoactive Substances (NPS)
Synthetic cannabinoids (SCs)

ASJC Scopus subject areas

Electronic, Optical and Magnetic Materials
Condensed Matter Physics
Computer Science Applications
Applied Mathematics
Electrical and Electronic Engineering

Access to Document

10.1117/12.2685133

Cite this

Kumar, R., Cozier, G. E., Andrews, R. C., & Pudney, C. R. (2023). Rapid detection of synthetic cannabinoids via fluorescence spectral fingerprints. In G. Lerondel, Y.-H. Cho, A. Taguchi, & S. Kawata (Eds.), UV and Higher Energy Photonics: From Materials to Applications 2023 Article 1265208 (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 12652). SPIE. https://doi.org/10.1117/12.2685133

Rapid detection of synthetic cannabinoids via fluorescence spectral fingerprints. / Kumar, R.; Cozier, Gyles E.; Andrews, Rachael C. et al.
UV and Higher Energy Photonics: From Materials to Applications 2023. ed. / Gilles Lerondel; Yong-Hoon Cho; Atsushi Taguchi; Satoshi Kawata. U. S. A.: SPIE, 2023. 1265208 (Proceedings of SPIE - The International Society for Optical Engineering; Vol. 12652).

Research output: Chapter or section in a book/report/conference proceeding › Chapter in a published conference proceeding

Kumar, R, Cozier, GE, Andrews, RC & Pudney, CR 2023, Rapid detection of synthetic cannabinoids via fluorescence spectral fingerprints. in G Lerondel, Y-H Cho, A Taguchi & S Kawata (eds), UV and Higher Energy Photonics: From Materials to Applications 2023., 1265208, Proceedings of SPIE - The International Society for Optical Engineering, vol. 12652, SPIE, U. S. A., UV and Higher Energy Photonics: From Materials to Applications 2023, San Diego, USA United States, 20/08/23. https://doi.org/10.1117/12.2685133

Kumar R, Cozier GE, Andrews RC, Pudney CR. Rapid detection of synthetic cannabinoids via fluorescence spectral fingerprints. In Lerondel G, Cho YH, Taguchi A, Kawata S, editors, UV and Higher Energy Photonics: From Materials to Applications 2023. U. S. A.: SPIE. 2023. 1265208. (Proceedings of SPIE - The International Society for Optical Engineering). Epub 2023 Oct 5. doi: 10.1117/12.2685133

Kumar, R. ; Cozier, Gyles E. ; Andrews, Rachael C. et al. / Rapid detection of synthetic cannabinoids via fluorescence spectral fingerprints. UV and Higher Energy Photonics: From Materials to Applications 2023. editor / Gilles Lerondel ; Yong-Hoon Cho ; Atsushi Taguchi ; Satoshi Kawata. U. S. A. : SPIE, 2023. (Proceedings of SPIE - The International Society for Optical Engineering).

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Rapid detection of synthetic cannabinoids via fluorescence spectral fingerprints

Abstract

Publication series

Conference

Bibliographical note

Funding

Keywords

ASJC Scopus subject areas

Access to Document

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