RADIOLABELED MOEM TYPE OLIGONUCLEOTIDES AND PROCESS FOR THEIR PREPARATION

Martin Edelmann (Inventor), Thorsten Muser (Inventor)

Research output: Patent

Abstract

The invention comprises radiolabeled MOEM type oligonucleotide of the formula (I), (I) wherein n, X1, X2, the linker (1), the linker (2), Q* and the receptor targeting moiety are as defined (I) the description. The radiolabeled oligonucleotides of the formula (I) can be used for the determination of the biodistribution and pharmacokinetics of the oligonucleotide in the tissue or body fluid.
Original languageEnglish
Patent numberWO/2020/254548
IPC C07H 1/00 2006.01,C07H 21/00 2006.01,G01N 33/60 2006.01,A61K 51/04 2006.01
Priority date20/06/20
Filing date19/06/20
Publication statusPublished - 24 Dec 2021

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