Abstract
The invention comprises radiolabeled MOEM type oligonucleotide of the formula (I), (I) wherein n, X1, X2, the linker (1), the linker (2), Q* and the receptor targeting moiety are as defined (I) the description. The radiolabeled oligonucleotides of the formula (I) can be used for the determination of the biodistribution and pharmacokinetics of the oligonucleotide in the tissue or body fluid.
Original language | English |
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Patent number | WO/2020/254548 |
IPC | C07H 1/00 2006.01,C07H 21/00 2006.01,G01N 33/60 2006.01,A61K 51/04 2006.01 |
Priority date | 20/06/20 |
Filing date | 19/06/20 |
Publication status | Published - 24 Dec 2021 |