Racial differences in the response of cardiorespiratory fitness to aerobic exercise training in Caucasian and African American postmenopausal women

Damon L. Swift, Neil M. Johannsen, Carl J. Lavie, Conrad P. Earnest, William D. Johnson, William D. Johnson, Timothy S. Church, Robert L. Newton

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Abstract

African American (AA) women have an elevated risk of cardiovascular disease and have been reported to have lower cardiorespiratory fitness (CRF) compared to Caucasian Americans (CA) women. However, little data exist evaluating racial differences in the change in CRF following aerobic exercise training. CA (n=264) and AA (n=122) postmenopausal women from the Dose Response to Exercise in Women study were randomized to 4, 8, 12 kilocalories per kg body weight per week (KKW) of aerobic training or the control group for six months. Cardiorespiratory fitness was evaluated using a cycle ergometer. A greater increase in relative CRF was observed in CA compared to AA women in the 4 (CA: 1.00 vs. AA: 0.35 mL O2*kg-1*min -1, p=0.034), 8 (CA: 1.59 vs. AA: 0.82 mL O2*kg-1*min -1, p=0.041) and 12KKW (CA: 1.98 vs. AA: 0.50 mL O2*kg-1*min -1, p=0.001) groups. Similar effects were found in absolute CRF with the exception of the 4KKW (CA: 0.04 vs. AA: 0.02, L O2/min, p=0.147) group. However, in categorical analyses, the percentages of women who improved both relative (>0 mL O2*kg-1*min -1) and absolute (>0 L O2/min) CRF were not significantly different for CA and AA participants in all exercise groups (all p>0.05). AA postmenopausal women in general had an attenuated increase in CRF (both relative and absolute) following exercise training, but had similar response rates compared to CA women. Future studies should investigate the physiologic mechanisms responsible for this attenuated response.
Original languageEnglish
Pages (from-to)1375-1382
JournalJournal of Applied Physiology
Volume114
Issue number10
Early online date9 Mar 2013
DOIs
Publication statusPublished - 15 May 2013

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African Americans
Exercise
Cardiorespiratory Fitness
Cardiovascular Diseases
Body Weight
Control Groups

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Racial differences in the response of cardiorespiratory fitness to aerobic exercise training in Caucasian and African American postmenopausal women. / Swift, Damon L.; Johannsen, Neil M.; Lavie, Carl J.; Earnest, Conrad P.; Johnson, William D.; Johnson, William D.; Church, Timothy S.; Newton, Robert L.

In: Journal of Applied Physiology, Vol. 114, No. 10, 15.05.2013, p. 1375-1382.

Research output: Contribution to journalArticle

Swift, Damon L. ; Johannsen, Neil M. ; Lavie, Carl J. ; Earnest, Conrad P. ; Johnson, William D. ; Johnson, William D. ; Church, Timothy S. ; Newton, Robert L. / Racial differences in the response of cardiorespiratory fitness to aerobic exercise training in Caucasian and African American postmenopausal women. In: Journal of Applied Physiology. 2013 ; Vol. 114, No. 10. pp. 1375-1382.
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abstract = "African American (AA) women have an elevated risk of cardiovascular disease and have been reported to have lower cardiorespiratory fitness (CRF) compared to Caucasian Americans (CA) women. However, little data exist evaluating racial differences in the change in CRF following aerobic exercise training. CA (n=264) and AA (n=122) postmenopausal women from the Dose Response to Exercise in Women study were randomized to 4, 8, 12 kilocalories per kg body weight per week (KKW) of aerobic training or the control group for six months. Cardiorespiratory fitness was evaluated using a cycle ergometer. A greater increase in relative CRF was observed in CA compared to AA women in the 4 (CA: 1.00 vs. AA: 0.35 mL O2*kg-1*min -1, p=0.034), 8 (CA: 1.59 vs. AA: 0.82 mL O2*kg-1*min -1, p=0.041) and 12KKW (CA: 1.98 vs. AA: 0.50 mL O2*kg-1*min -1, p=0.001) groups. Similar effects were found in absolute CRF with the exception of the 4KKW (CA: 0.04 vs. AA: 0.02, L O2/min, p=0.147) group. However, in categorical analyses, the percentages of women who improved both relative (>0 mL O2*kg-1*min -1) and absolute (>0 L O2/min) CRF were not significantly different for CA and AA participants in all exercise groups (all p>0.05). AA postmenopausal women in general had an attenuated increase in CRF (both relative and absolute) following exercise training, but had similar response rates compared to CA women. Future studies should investigate the physiologic mechanisms responsible for this attenuated response.",
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