Racemic auxiliaries: applications to asymmetric synthesis

C Neri, J M J Williams

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6 Citations (Scopus)

Abstract

Racemic auxiliaries have been successfully used to achieve asymmetric synthesis. Racemic Evans aldol products were obtained from racemic acyl oxazolidinones with good diastereocontrol. The enantiomers of the racemic aldol products were resolved by a lipase-catalysed acylation reaction. Hydrolysis afforded enantiomerically enriched oxazolidinones and enantiomerically enriched beta-hydroxy acids. (C) 2002 Published by Elsevier Science Ltd.
Original languageEnglish
Pages (from-to)4257-4260
Number of pages4
JournalTetrahedron Letters
Volume43
Issue number23
Publication statusPublished - 2002

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    Neri, C., & Williams, J. M. J. (2002). Racemic auxiliaries: applications to asymmetric synthesis. Tetrahedron Letters, 43(23), 4257-4260.