Abstract
Racemic auxiliaries have been successfully used to achieve asymmetric synthesis. Racemic Evans aldol products were obtained from racemic acyl oxazolidinones with good diastereocontrol. The enantiomers of the racemic aldol products were resolved by a lipase-catalysed acylation reaction. Hydrolysis afforded enantiomerically enriched oxazolidinones and enantiomerically enriched beta-hydroxy acids. (C) 2002 Published by Elsevier Science Ltd.
| Original language | English |
|---|---|
| Pages (from-to) | 4257-4260 |
| Number of pages | 4 |
| Journal | Tetrahedron Letters |
| Volume | 43 |
| Issue number | 23 |
| Publication status | Published - 2002 |