Rabbit muscle glycogen phosphorylase b. the structural basis of activation and catalysis

Nikos G. Oikonomakos, K. Ravi Acharya, Louise N. Johnson

Research output: Chapter or section in a book/report/conference proceedingChapter or section

19 Citations (SciVal)

Abstract

Post-Translational Modifications of Proteins discusses several important topics of interest to researchers and students in protein chemistry and biochemistry, including the occurrence and function of hydroxylated residues and the three enzymes required for their formation; the damaging effects of reactions between sugars and proteins; ADP-riboosylation of proteins outside the nucleus; and Monod, Wyman, and Changeux's concerted model for allosteric control of enzyme activity exemplified by studies on glycogen phosphorylase. The application of Fast Atom Bombardment Mass Spectometry (FAB-MS) to studies on the structure and biosynthesis of various oligosaccharide moieties in protein is examined, and the understanding of the structural diversity and function of glycoprotein oligosaccharides is discussed in this volume.
Original languageEnglish
Title of host publicationPost-translational Modifications of Proteins
EditorsJohn J. Harding, M. James C. Crabbe
Place of PublicationBoca Raton, U. S. A.
PublisherCRC Press
Pages81-151
Number of pages71
ISBN (Electronic)9781040291702
ISBN (Print)9780849341717
DOIs
Publication statusPublished - 13 Dec 1991

ASJC Scopus subject areas

  • General Medicine
  • General Biochemistry,Genetics and Molecular Biology
  • General Pharmacology, Toxicology and Pharmaceutics
  • General Agricultural and Biological Sciences

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