@article{f8479e2603fa4d3aae9b59c845dc0d6a,
title = "Quantification of biomarker functionality predicts patient outcomes",
abstract = "Implementation of a quantitative molecular imaging method (iFRET), which determines receptor–ligand interactions, has led to the finding that patients with a low extent of PD-1/PD-L1 interaction in metastatic NSCLC, and malignant melanoma, display significantly worsened overall survival compared to those with a high level of interaction.",
author = "Banafsh{\'e} Larijani and James Miles and Ward, {Stephen G.} and Parker, {Peter J.}",
note = "Funding Information: Funding information The original research was supported, in part, by Department of Education, Basque Government-IT1270-19, Elkartek grant (BG18) and the Spanish Ministry grant (MINECO) PROJECTS of EXCELLENCE (BFU2015-65625-P). P.J.P. was supported by a core grant to the Francis Crick Institute, from Cancer Research UK (FC001130), the UK Medical Research Council (FC001130) and the Wellcome Trust (FC001130). ",
year = "2021",
month = may,
day = "11",
doi = "10.1038/s41416-021-01291-3",
language = "English",
volume = "124",
pages = "1618--1620",
journal = "British Journal of Cancer",
issn = "0007-0920",
publisher = "Nature Research",
number = "10",
}
