Quantification of biomarker functionality predicts patient outcomes

Banafshé Larijani, James Miles, Stephen G. Ward, Peter J. Parker

Research output: Contribution to journalComment/debatepeer-review

Abstract

Implementation of a quantitative molecular imaging method (iFRET), which determines receptor–ligand interactions, has led to the finding that patients with a low extent of PD-1/PD-L1 interaction in metastatic NSCLC, and malignant melanoma, display significantly worsened overall survival compared to those with a high level of interaction.

Original languageEnglish
JournalBritish Journal of Cancer
Early online date15 Mar 2021
DOIs
Publication statusE-pub ahead of print - 15 Mar 2021

ASJC Scopus subject areas

  • Oncology
  • Cancer Research

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