Public funds and local biotechnology firm creation

Christos Kolympiris, Nicholas Kalaitzandonakes, Douglas Miller

Research output: Contribution to journalArticlepeer-review

20 Citations (SciVal)


A long stream of academic literature has established that public funding towards research and development matters for economic growth because it relates to increases in innovation, productivity and the like. The impact of public funding on the creation of new firms has received less attention in this literature despite theoretical constructs that support such association. In the present paper we study whether indeed there is a relationship between public research funds and local firm births in the context of the U.S. biotechnology industry. In doing so, we introduce a number of changes that strengthen the robustness of our findings when compared with existing literature. These changes include a direct measure of research expenditures and a considerably lengthier longitudinal dataset which allows us to capture a structural relationship and not a chance event. We empirically demonstrate that increases in the level of research funding from the National Institutes of Health towards biotechnology associate with increases in the number of biotechnology firm births at the Metropolitan Statistical Area level. Further, we reveal that public funds towards established firms associate with local firm births considerably more strongly when compared with funds towards universities and research institutes/hospitals. We conclude the paper with academic and policy implications of the present work that highlight the complexity of factors that underlie the creation of local firms in high technology industries. JEL classification*C23*L26*O18*R3*R12.

Original languageEnglish
Pages (from-to)121-137
Number of pages17
JournalResearch Policy
Issue number1
Early online date24 Aug 2013
Publication statusPublished - 1 Feb 2014


  • Biotechnology
  • Federal funding
  • Firm birth
  • MSA
  • NIH


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