Proximity effects in 1-azaspirocyclo[5.5]undecanes. X-ray structure determination of a diol derivative

Andrew B. Holmes; Paul R. Raithby; Maria J. Rosales; Keith Russell; Edward S. Stern; Michael E. Stubbs

doi:10.1016/S0040-4039(01)91417-0

Proximity effects in 1-azaspirocyclo[5.5]undecanes. X-ray structure determination of a diol derivative

Andrew B. Holmes, Paul R. Raithby, Maria J. Rosales, Keith Russell, Edward S. Stern, Michael E. Stubbs

Research output: Contribution to journal › Article › peer-review

Abstract

Neighbouring group participation is used to control bromination of the alkene (1) to give the bromo-acetate (3) which is converted into the diol (6a) [characterised by X-ray structure determination of the cyclic carbamate (8)] and the epoxide (2).

Original language	English
Pages (from-to)	5705-5708
Number of pages	4
Journal	Tetrahedron Letters
Volume	25
Issue number	49
DOIs	https://doi.org/10.1016/S0040-4039(01)91417-0
Publication status	Published - 1984

ASJC Scopus subject areas

Biochemistry
Drug Discovery
Organic Chemistry

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10.1016/S0040-4039(01)91417-0

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title = "Proximity effects in 1-azaspirocyclo[5.5]undecanes. X-ray structure determination of a diol derivative",

abstract = "Neighbouring group participation is used to control bromination of the alkene (1) to give the bromo-acetate (3) which is converted into the diol (6a) [characterised by X-ray structure determination of the cyclic carbamate (8)] and the epoxide (2).",

author = "Holmes, \{Andrew B.\} and Raithby, \{Paul R.\} and Rosales, \{Maria J.\} and Keith Russell and Stern, \{Edward S.\} and Stubbs, \{Michael E.\}",

year = "1984",

doi = "10.1016/S0040-4039(01)91417-0",

language = "English",

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journal = "Tetrahedron Letters",

issn = "0040-4039",

publisher = "Elsevier",

number = "49",

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T1 - Proximity effects in 1-azaspirocyclo[5.5]undecanes. X-ray structure determination of a diol derivative

AU - Holmes, Andrew B.

AU - Raithby, Paul R.

AU - Rosales, Maria J.

AU - Russell, Keith

AU - Stern, Edward S.

AU - Stubbs, Michael E.

PY - 1984

Y1 - 1984

N2 - Neighbouring group participation is used to control bromination of the alkene (1) to give the bromo-acetate (3) which is converted into the diol (6a) [characterised by X-ray structure determination of the cyclic carbamate (8)] and the epoxide (2).

AB - Neighbouring group participation is used to control bromination of the alkene (1) to give the bromo-acetate (3) which is converted into the diol (6a) [characterised by X-ray structure determination of the cyclic carbamate (8)] and the epoxide (2).

UR - https://www.scopus.com/pages/publications/48749136410

U2 - 10.1016/S0040-4039(01)91417-0

DO - 10.1016/S0040-4039(01)91417-0

M3 - Article

AN - SCOPUS:48749136410

SN - 0040-4039

VL - 25

SP - 5705

EP - 5708

JO - Tetrahedron Letters

JF - Tetrahedron Letters

IS - 49

ER -

Proximity effects in 1-azaspirocyclo[5.5]undecanes. X-ray structure determination of a diol derivative

Abstract

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