Protease detection assay

Stephen Flower; Helen Braven; Russell Keay

Protease detection assay

Stephen Flower (Inventor)
, Helen Braven (Inventor)
, Russell Keay (Inventor)

Department of Chemistry

Atlas Genetics Ltd

Research output: Patent

Abstract

The invention provides methods and compounds for detecting protease activity in a sample solution comprising contacting the sample solution with a protease substrate labeled with an electrochemically active marker, providing conditions under which any protease which may be present in the sample may degrade the protease substrate and electrochemically determining information relating to the electrochemically active marker.

Original language	English
Patent number	20100320093
IPC	C07F15/00
Publication status	Published - 23 Dec 2010

Keywords

Electrochemical
assay
molecular biology
protease detection

Cite this

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title = "Protease detection assay",

abstract = "The invention provides methods and compounds for detecting protease activity in a sample solution comprising contacting the sample solution with a protease substrate labeled with an electrochemically active marker, providing conditions under which any protease which may be present in the sample may degrade the protease substrate and electrochemically determining information relating to the electrochemically active marker.",

keywords = "Electrochemical, assay, molecular biology, protease detection",

author = "Stephen Flower and Helen Braven and Russell Keay",

year = "2010",

month = dec,

day = "23",

language = "English",

type = "Patent",

note = "20100320093; C07F15/00",

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TY - PAT

T1 - Protease detection assay

AU - Flower, Stephen

AU - Braven, Helen

AU - Keay, Russell

PY - 2010/12/23

Y1 - 2010/12/23

N2 - The invention provides methods and compounds for detecting protease activity in a sample solution comprising contacting the sample solution with a protease substrate labeled with an electrochemically active marker, providing conditions under which any protease which may be present in the sample may degrade the protease substrate and electrochemically determining information relating to the electrochemically active marker.

AB - The invention provides methods and compounds for detecting protease activity in a sample solution comprising contacting the sample solution with a protease substrate labeled with an electrochemically active marker, providing conditions under which any protease which may be present in the sample may degrade the protease substrate and electrochemically determining information relating to the electrochemically active marker.

KW - Electrochemical

KW - assay

KW - molecular biology

KW - protease detection

UR - http://worldwide.espacenet.com/publicationDetails/biblio?CC=US&NR=2010320093A1&KC=A1&FT=D&ND=3&date=20101223&DB=EPODOC&locale=en_EP

M3 - Patent

M1 - 20100320093

ER -

Protease detection assay

Abstract

Keywords

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