Prolonged vitamin C supplementation and recovery from demanding exercise

D Thompson, C Williams, S J McGregor, C W Nicholas, F McArdle, M J Jackson, J R Powell

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The aim of the present study was to investigate whether 2 weeks of vitamin C supplementation affects recovery from an unaccustomed bout of exercise. Sixteen male subjects were allocated to either a placebo (P; n = 8) or vitamin C group (VC; n = 8). The VC group consumed 200 mg of ascorbic acid twice a day, whereas the P group consumed identical capsules containing 200 mg of lactose. Subjects performed a prolonged (90-min) intermittent shuttle-running test 14 days after supplementation began. Post-exercise serum creatine kinase activities and myoglobin concentrations were unaffected by supplementation. However, vitamin C supplementation had modest beneficial effects on muscle soreness, muscle function, and plasma concentrations of malondialdehyde. Furthermore, although plasma interleukin-6 increased immediately after exercise in both groups, values in the VC group were lower than in the P group 2 hours after exercise (p < .05). These results suggest that prolonged vitamin C supplementation has some modest beneficial effects on recovery from unaccustomed exercise.
Original languageEnglish
Pages (from-to)466-481
Number of pages16
JournalInternational Journal of Sport Nutrition and Exercise Metabolism
Issue number4
Publication statusPublished - 2001


Cite this

Thompson, D., Williams, C., McGregor, S. J., Nicholas, C. W., McArdle, F., Jackson, M. J., & Powell, J. R. (2001). Prolonged vitamin C supplementation and recovery from demanding exercise. International Journal of Sport Nutrition and Exercise Metabolism, 11(4), 466-481.