Production of cello-oligosaccharides through the biorefinery concept: A technical-economic and life-cycle assessment

Fernando C. Barbosa, Guilherme P. Nogueira, Emanuele Kendrick, Telma T. Franco, David Leak, Mariana O.S. Dias, Carla K.N. Cavaliero, Rosana Goldbeck

Research output: Contribution to journalArticlepeer-review

3 Citations (SciVal)


Producers look for co-products to increase the value chain and production flexibility. With a high market aggregate value, the production of cello-oligosaccharides (COS) as functional oligosaccharides from cellulosic substrates has been investigated. As COS/cellopentaose production process are rarely described in the literature, this study estimated the cellopentaose production cost and performed a life-cycle assessment of the cellopentaose production process previously developed using sugarcane straw as a substrate. The results demonstrated that, through the six scenarios studied, it was possible to obtain a cellopentaose unit production cost varying between USD 0.40 and 1.15/mg, and that optimization in the upstream sector can reduce the total plant direct cost and the overall life-cycle impact. The results also suggested that a better understanding of the hydrolysis solid/liquid proportion is necessary to reduce the bulk material cost. An environmental impact reduction of between 16.2% and 19.9% was also observed. In terms of the integrated biorefinery concept, sugarcane straw fermentation represents a prospective technology for the production of COS.

Original languageEnglish
Pages (from-to)1763-1774
Number of pages12
JournalBiofuels, Bioproducts and Biorefining
Issue number6
Early online date16 Aug 2021
Publication statusPublished - 1 Nov 2021


  • bioprocess
  • biorefinery
  • cello-oligosaccharides
  • life cycle
  • sugarcane straw
  • techno-economic

ASJC Scopus subject areas

  • Bioengineering
  • Renewable Energy, Sustainability and the Environment


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